Assuntos
Acrodermatite/diagnóstico , Inibidor de Coagulação do Lúpus/sangue , Doença de Lyme/diagnóstico , Acrodermatite/sangue , Acrodermatite/microbiologia , Complexo Antígeno-Anticorpo/sangue , Atrofia , Doença Crônica , Feminino , Humanos , Hipergamaglobulinemia/sangue , Hipergamaglobulinemia/diagnóstico , Imunoglobulina G/sangue , Cadeias lambda de Imunoglobulina/sangue , Doença de Lyme/sangue , Pessoa de Meia-IdadeAssuntos
Anticorpos Antinucleares/imunologia , Proteínas Cromossômicas não Histona , Linfadenite Histiocítica Necrosante/imunologia , Proteínas Oncogênicas/imunologia , Adulto , Anticorpos Antinucleares/análise , Humanos , Imunoensaio , Linfadenite/imunologia , Proteínas Oncogênicas/análise , Proteínas de Ligação a Poli-ADP-RiboseAssuntos
Neoplasias Ósseas/complicações , Neoplasias da Mama/patologia , Carcinoma/patologia , Síndrome do Desconforto Respiratório/etiologia , Vasculite/complicações , Neoplasias Ósseas/radioterapia , Neoplasias Ósseas/secundário , Evolução Fatal , Feminino , Humanos , Pessoa de Meia-Idade , Vasculite/patologiaRESUMO
OBJECTIVES: An abbreviated 2-1-1 schedule for post-exposure rabies vaccination would theoretically lead to more rapid production of specific antibodies than the classical schedule. We measured early serological response to the 2-1-1 schedule. METHODS: Patients consulting the antirabies centre of the Epinal hospital from June 1992 to June 1993 who had never been vaccinated and whose exposure history justified antirabies vaccination were included in this study. Fifty subjects were vaccinated with PVRV (purified vero rabies vaccine, Pasteur Institute) cultured on VERO (vervet monkey origin) cells using the abbreviated 2-1-1 schedule of 2 doses (0.5 ml = 2.5 IU/dose) on day 0 and 1 dose on days 7 and 21. Antirabies antibodies were assayed using the Platelia Rage immunoenzyme method (Diagnostic Pasteur) on day 21. Titres above 0.5 IU were considered to give protection and non-protected subjects were seen again on day 28 for a supplementary dose. RESULTS: Only 34 subjects (68%) had protective antibody titres on day 21, but by day 28, 48 (96%) had acquired immunity. In this study population, the age range was from 1 to 83 years and age over 30 years appeared to delay antibody formation. CONCLUSION: These findings emphasize the importance of initial antirabies immunoglobulins if short incubation in suspected and the need for serological follow-up if delayed antibody formation is suspected (subjects over 30).
Assuntos
Anticorpos Antivirais/análise , Vacina Antirrábica/administração & dosagem , Vírus da Raiva/imunologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Células Cultivadas , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Vacina Antirrábica/imunologia , Fatores de TempoRESUMO
Streptococcus anginosus, the term suggested to cover a set of streptococci previously known under various names (milleri, MG, anginosus, intermedius, constellatus), is characterized by a propensity to create parenchymatous abscesses, essentially cerebral or hepatic, particularly within the terms of septicemia. These abscesses are sometimes difficult to detect due to a difficult or non-existent symptomatology. The authors report on four cases illustrating the necessity to search for them systematically by cerebral CT scan and abdominal echography or CT scan in all cases of septicemia caused by Streptococcus anginosus.
Assuntos
Bacteriemia/complicações , Abscesso Encefálico/microbiologia , Abscesso Hepático/microbiologia , Infecções Estreptocócicas/complicações , Idoso , Abscesso Encefálico/diagnóstico por imagem , Humanos , Abscesso Hepático/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios X , UltrassonografiaRESUMO
During one year from July 1992 to July 1993, we performed usual hemostasis tests in a population or 3,700 patients. We found 12 patients with a lupus like anticoagulant (incidence: 1/1,000). Among these 12, four had unexplained polyneuropathy or myélopathy. Lupus like anticoagulant was either isolated (two cases), either associated with thrombosis (two cases). We report these four cases and we discuss the causal or uncasual nature of this association.