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1.
Foot Ankle Surg ; 26(5): 551-555, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31371267

RESUMO

BACKGROUND: Percutaneous osteotomy of calcaneus has been proposed to reduce the complication rate and became more and more popular. The bone cut can be performed as a straight or chevron-like (V) osteotomy using a Shannon burr. Comparative studies of straight or V-osteotomy as like as one or two screws in percutaneous calcaneal osteotomies are missing in the literature. We hypothesize that the V-osteotomy will result in a higher stiffness in biomechanical testing as the straight osteotomy using single screw for fixation. METHODS: The straight osteotomy (9 fresh-frozen specimens) and V-osteotomy (9 fresh-frozen specimens) was performed and the calcaneal tuberosity was moved 10mm medially and slightly rotated. One 6,5mm cancellous compression screw was used for osteosynthesis. Specimens were preconditioned with 100N over 100 cycles. The force was increased after every 100N by 100N from 200 to 500N. This was followed by cyclic loading with 600N for 500 cycles. RESULTS: Despite the higher mean values of the group with V-osteotomy, no significant difference was registered between the two groups regarding the stiffness at all force levels. A higher failure rate was observed in the group with straight osteotomy. CONCLUSION: The moderate correlation of bone density and stiffness in the V-group, and significantly lower failure rate with no secondary dislocation in fluoroscopy indicates the superiority of the V-osteotomy in the present study. Whether the demonstrated advantages can be reflected in clinical practice should be investigated in further studies. LEVEL OF CLINICAL EVIDENCE: 5.


Assuntos
Parafusos Ósseos , Calcâneo/cirurgia , Fixação Interna de Fraturas/métodos , Osteotomia/métodos , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Calcâneo/fisiopatologia , Feminino , Humanos , Masculino , Pressão
2.
Praxis (Bern 1994) ; 99(24): 1507-11, 2010 Dec 01.
Artigo em Francês | MEDLINE | ID: mdl-21125536

RESUMO

An 88 years old woman was admitted for muscular pain and weakness. She was under a treatment of simvastatin and was recently prescribed clarithromycin for a lung infection. The diagnosis of statin induced rhabdomyolysis by drug interaction was made. The evolution is good with eviction of the statin and aggressive hydratation. This case shows how important it is to know the risks factors and drug interactions predisposing to statin-induced myopathy.


Assuntos
Antibacterianos/efeitos adversos , Anticolesterolemiantes/efeitos adversos , Claritromicina/efeitos adversos , Debilidade Muscular/induzido quimicamente , Dor/induzido quimicamente , Rabdomiólise/induzido quimicamente , Rabdomiólise/diagnóstico , Sinvastatina/efeitos adversos , Idoso de 80 Anos ou mais , Antibacterianos/uso terapêutico , Anticolesterolemiantes/uso terapêutico , Claritromicina/uso terapêutico , Diagnóstico Diferencial , Interações Medicamentosas , Quimioterapia Combinada , Feminino , Humanos , Sinvastatina/uso terapêutico
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