Impression Disinfection and Its Effect on Dimensional Accuracy and Surface Detail in the Times of COVID-19: An In Vitro Study.

Introduction The disinfection of impressions is crucial to eliminate the viral and other microbial loads to prevent the cross contamination of diseases. The aim of this study was to compare the effect of different virucidal disinfecting methods on the dimensional accuracy and surface detail reproduction (SDR) of impression materials. Methods A total of 160 samples were fabricated with different impression materials using zinc oxide eugenol (Group 1), alginate (Group 2), polyether (Group 3), and addition silicone (Group 4) impression materials, each containing 40 samples (n=40). These groups were further divided into Subgroups A, B, C, and D (n=10) based on the disinfecting method used. Disinfection was carried out using 0.2% peracetic acid (A), a natural polymer of glucosamine (B), ultraviolet (UV) radiation (C), and ozonated water (D). The disinfected impressions were poured in type IV gypsum, and the obtained casts were checked for dimensional accuracy and surface detail reproduction (SDR). For dimensional accuracy, a one-way analysis of variance (ANOVA) test and, for surface detail reproduction, the chi-square test were used to compare the different subgroups of each impression material separately. Results Zinc oxide eugenol samples showed the lowest mean dimensional change when disinfected with 0.2% peracetic acid (1A=154.1 µm), and alginate showed the lowest mean dimensional change when disinfected using ozonated water (2D=134.9 µm). On the other hand, the lowest mean dimensional change observed in polyether and addition silicone samples was those which were disinfected using UV radiation (3C=100.9 µm and 4C=113.5 µm). Surface detail was reproduced adequately in most of the samples. Conclusion A 0.2% peracetic acid could be used to disinfect zinc oxide eugenol impressions, ozonated water for alginate impressions, and UV radiation for polyether and addition silicone impressions.

Effect of ALDH1A1 and CD44 on Survival and Disease Recurrence in Patients With Osteosarcoma.

PURPOSE: Emerging evidence suggests that osteosarcoma stem cells (OSCs) may be responsible for tumor initiation propagation, recurrence, and resistance to therapy. We set out to evaluate the relationship between the abundance of ALDH1A1 and CD44-positive cells in biopsy and resection samples on disease recurrence and overall survival. METHODS: A retrospective review of 20 patients, including biopsy and resection samples, was performed at a comprehensive cancer center. Additionally, we queried the publicly available TARGET dataset of osteosarcoma patients. RESULTS: Neither the percentages of ALDH1A1-positive cells nor CD44-positive cells were significantly associated with overall mortality or disease recurrence in either biopsy or resection samples. Unlike our institutional data, overall survival was significantly correlated to higher ALDH1A1 expression in the TARGET dataset both in univariate and age-adjusted analyses. CONCLUSIONS: ADLH1 and CD44, potential markers of OSCs, were not found to be reliable clinical immunohistochemical prognostic markers for osteosarcoma patient survival, specifically disease-free survival. Osteosarcoma patients with high ALDH1A1 RNA expression showed improved overall survival in examining a national genomic database of osteosarcoma patients but again no association with disease-free survival. The potential of CD44 and ALDH1A1 as cellular-specific prognostic markers of survival, and as possible molecular targets, may be limited in osteosarcoma.

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.

OBJECTIVE: To systematically review the association of pain, function, and progression in first carpometacarpal (CMC) osteoarthritis (OA) with imaging biomarkers and radiography-based staging. DESIGN: Database searches in PubMed, Embase, and the Cochrane Library, along with citation searching were conducted in accordance with published guidance. Data on the association of imaging with pain, functional status, and disease progression were extracted and synthesized, along with key information on study methodology such as sample sizes, use of control subjects, study design, number of image raters, and blinding. Methodological quality was assessed using National Heart, Lung, and Blood Institute tools. RESULTS: After duplicate removal, a total of 1969 records were screened. Forty-six articles are included in this review, covering a total of 28,202 study participants, 7263 with first CMC OA. Osteophytes were found to be one of the strongest biomarkers for pain across imaging modalities. Radiographic findings alone showed conflicting relationships with pain. However, Kellgren-Lawrence staging showed consistent associations with pain in various studies. Radiographic, sonographic, and MRI findings and staging showed little association to tools evaluating functional status across imaging modalities. The same imaging methods showed limited ability to predict progression of first CMC OA. A major limitation was the heterogeneity in the study base, limiting synthesis of results. CONCLUSION: Imaging findings and radiography-based staging systems generally showed strong associations with pain, but not with functional status or disease progression. More research and improved imaging techniques are needed to help physicians better manage patients with first CMC OA.

Study of lipid profile in young patients (age 40 years or below) with acute coronary syndrome.

Background: Acute coronary syndrome (ACS) refers to a group of clinical symptoms compatible with acute myocardial ischemia and includes unstable angina, non-ST segment elevation myocardial infarction and ST-segment elevation myocardial infarction. Aims and Objectives: To study the incidence of lipid profile abnormalities in young patients (age 40 years or below) with ACS with clinical and cardiovascular risk profile. Material and Methods: The study was conducted on 223 young patients of acute coronary syndrome with age 40 years or below. 89 young patients with acute coronary syndrome having lipid abnormalities were further followed up after 1 month. Results: Majority of patients (55.15%) in the study population belonged to 35-40 years age group. Mean age of study population was 35.65 + 4.62 years with 90.13% males and 9.86% females. Main presenting symptom was precordial chest pain in 93.72% patients. Smoking was the commonest risk factor in young adults (81.7%). Other risk factors like diabetes, hypertension, family history were less common in young adults. Drug addiction was also higher in younger population (16%). Majority of young adults with acute coronary syndrome had more than 1 (47.53%) risk factor. Majority of patients were in Killip class I (86.9%) and only few patients (13.1%) had Killip class II or above. ST elevation myocardial infarction was far more common than NTEMI/USA and was found in 164 (73.5%) patients. Most common type of infarction was anterior wall myocardial infarction (62.80%). Majority of young patients had negative TMT, so it suggests that ACS in younger population has lesser complications during presentation, hospital stay and on follow-up. Conclusion: ACS in young continues to increase in Indian subcontinent. Younger patient with an ACS have different clinical characteristics and a different prognosis than older patients. The extent of CAD and degree of myocardial necrosis has influence on presentation and subsequent MACE in ACS and in this study, it appears dyslipidemia do not play any significant role in influencing extent of CAD and has little effect on outcome whether during acute stage or on immediate follow-up after ACS.

Underrepresentation of Racial and Ethnic Diversity in Research Informing the American Urological Association/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Stress Urinary Incontinence Guideline.

OBJECTIVE: To characterize the racial/ethnic representation in the studies used in the American Urological Association/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction stress urinary incontinence guideline. METHODS: Cited studies were reviewed using inclusion and exclusion criteria. The inclusion criteria focused on United States literature to allow for demographic comparison with census data. To compare the racial representation in a study to the diversity in the surrounding city, we calculated the differences between county census data and the study race reported data and performed regression analyses. RESULTS: Eighty-seven cited studies were reviewed, of which 33 were excluded and 52 studies were further evaluated. Seventeen studies were US studies, nine of which reported race. Eighty percent of the women included in the 9 studies were non-Hispanic white women. A diverse geographic region did not correlate with increased study enrollment of non-White patients. CONCLUSION: The majority of cited studies used to develop the stress urinary incontinence management guidelines did not report the race/ethnicity of participants. Among those studies that did, Asian, Black, and Hispanic women were included at lower rates than non-Hispanic white women, identifying an area of opportunity to improve research recruitment and promote health equity. Non-Hispanic women were consistently overrepresented while other women were either under-represented or completely excluded.

Early ABI Testing May Decrease Risk of Amputation for Patients With Lower Extremity Ulcers.

BACKGROUND: Patients with lower extremity wounds from diabetes mellitus or peripheral artery disease (PAD) have a risk of amputation as high as 25%. In patients with arterial disease, revascularization decreases the risk of amputation. We aimed to determine if the early assessment of arterial perfusion correlates with the risk of amputation. METHODS: We retrospectively reviewed patients referred to the vascular clinic over 18 months with Rutherford Grade 5 and 6 chronic limb-threatening ischemia to determine if patients had a pulse exam done at the time the wound was identified and when ankle brachial index (ABI) testing to evaluate perfusion was performed. Kaplan Meier analysis was used to determine if the timing of ABI testing affected the time to revascularization, wound healing, and risk of amputation. RESULTS: Ninety-three patients with lower extremity wounds were identified. Of these, 59 patients (63%) did not have a pulse exam performed by their primary care provider when the wound was identified. Patients were classified by when they underwent ankle brachial index testing to assess arterial perfusion. Twenty-four had early ABI (<30 days) testing, with the remaining 69 patients having late ABI testing. Patients in the early ABI group were more likely to have a pulse exam done by their PCP than those in the late group, 12 (50%) vs. 22 (32%), P = 0.03. Early ABI patients had a quicker time to vascular referral (13 days vs. 91 days, P < 0.001). Early ABI patients also had quicker times to wound healing than those in the late group (117 days vs. 287 days, P < 0.001). Finally, patients that underwent early ABI were less likely to require amputation (Fig. 1), although this did not reach statistical significance (P = 0.07). CONCLUSIONS: Early ABI testing expedites specialty referral and time to revascularization. It can decrease the time to wound healing. Larger cohort studies are needed to determine the overall effect of early ABI testing to decrease amputation rates.

Outcomes of the Supris Sling in an Urban Latina Population.

OBJECTIVE: To analyze patient reported outcomes, safety, and efficacy of the Supris mid-urethral sling in a diverse population. METHODS: A retrospective chart review of 101 women who underwent a mid-urethral Suprissling procedure was conducted. Baseline characteristics and perioperative parameters were collected. Post-operative results and patient reported outcomes were collected at an average follow-up time of 19 months using the Urogenital Distress Inventory-6 (UDI-6) and Patient Global Impression of Improvement (PGI-I) validated questionnaires. Subjective cure rates were compared using the nonparametric Wilcoxon Rank Sum Test. RESULTS: The median age of women was 57 years old, and 86.1% identified as Latina. 28% and 72% of women had a SUI and MUI diagnosis, respectively. Women, on average, used 2 pads pre-operatively and none post-operatively. There was a 3% surgical revision rate. 80 women completed the questionnaires. 82% of the MUI group reported being very much improved or much better. The SUI group reported being 94% very much improved or much better. The UDI-6 questions related to urgency and leakage of small amounts of urine were significantly different between the MUI and SUI groups (P = .002 and P = .044). CONCLUSION: In our primarily Latina patient population, the majority of whom had MUI, the Supris retropubic sling greatly improved symptoms. Although reported outcomes were excellent in both groups, those with pre-operative urge incontinence were more likely to experience urge symptoms post-operatively. Despite persistent urge symptoms, patients reported improvement of their overall symptoms.

Prediction of groundwater nitrate concentration in a semiarid region using hybrid Bayesian artificial intelligence approaches.

Nitrate is a major pollutant in groundwater whose main source is municipal wastewater and agricultural activities. In the present study, Bayesian approaches such as Bayesian generalized linear model (BGLM), Bayesian regularized neural network (BRNN), Bayesian additive regression tree (BART), and Bayesian ridge regression (BRR) were used to model groundwater nitrate contamination in a semiarid region Marvdasht watershed, Fars province, Iran. Eleven groundwater (GW) nitrate conditioning factors have been taken as input parameters for predictive modeling. The results showed that the Bayesian models used in this study were all competent to model groundwater nitrate and the BART model with R2 = 0.83 was more efficient than the other models. The result of variable importance showed that potassium (K) has the highest importance in the models followed by rainfall, altitude, groundwater depth, and distance from the residential area. The results of the study can support the decision-making process to control and reduce the sources of nitrate pollution.

Study on Evolution of Micropipes from Hexagonal Voids in 4H-SiC Crystals by Cathodoluminescence Imaging.

This paper presents an investigation on micropipe evolution from hexagonal voids in physical vapor transport-grown 4H-SiC single crystals using the cathodoluminescence (CL) imaging technique. Complementary techniques optical microscopy, scanning electron microscopy, and energy-dispersive spectroscopy (EDS) are also used to understand the formation mechanism of hexagonal voids along with the origin of pipes from these voids. The ability of CL to image variations along the depth of the sample provides new insights on how micropipes are attached to hexagonal voids that lie deep within the bulk single crystals. CL imaging confirms that multiple micropipes can originate from a single hexagonal void. EDS mapping shows that the inside of the micropipe walls exhibits higher levels of carbon. Investigation of the seed region by optical imaging shows that improper fixing of the seed to the crucible lid is the root cause for the formation of hexagonal voids that subsequently lead to micropipe formation.

Flash-Flood Potential Mapping Using Deep Learning, Alternating Decision Trees and Data Provided by Remote Sensing Sensors.

There is an evident increase in the importance that remote sensing sensors play in the monitoring and evaluation of natural hazards susceptibility and risk. The present study aims to assess the flash-flood potential values, in a small catchment from Romania, using information provided remote sensing sensors and Geographic Informational Systems (GIS) databases which were involved as input data into a number of four ensemble models. In a first phase, with the help of high-resolution satellite images from the Google Earth application, 481 points affected by torrential processes were acquired, another 481 points being randomly positioned in areas without torrential processes. Seventy percent of the dataset was kept as training data, while the other 30% was assigned to validating sample. Further, in order to train the machine learning models, information regarding the 10 flash-flood predictors was extracted in the training sample locations. Finally, the following four ensembles were used to calculate the Flash-Flood Potential Index across the Bâsca Chiojdului river basin: Deep Learning Neural Network-Frequency Ratio (DLNN-FR), Deep Learning Neural Network-Weights of Evidence (DLNN-WOE), Alternating Decision Trees-Frequency Ratio (ADT-FR) and Alternating Decision Trees-Weights of Evidence (ADT-WOE). The model's performances were assessed using several statistical metrics. Thus, in terms of Sensitivity, the highest value of 0.985 was achieved by the DLNN-FR model, meanwhile the lowest one (0.866) was assigned to ADT-FR ensemble. Moreover, the specificity analysis shows that the highest value (0.991) was attributed to DLNN-WOE algorithm, while the lowest value (0.892) was achieved by ADT-FR. During the training procedure, the models achieved overall accuracies between 0.878 (ADT-FR) and 0.985 (DLNN-WOE). K-index shows again that the most performant model was DLNN-WOE (0.97). The Flash-Flood Potential Index (FFPI) values revealed that the surfaces with high and very high flash-flood susceptibility cover between 46.57% (DLNN-FR) and 59.38% (ADT-FR) of the study zone. The use of the Receiver Operating Characteristic (ROC) curve for results validation highlights the fact that FFPIDLNN-WOE is characterized by the most precise results with an Area Under Curve of 0.96.

Optimization of state-of-the-art fuzzy-metaheuristic ANFIS-based machine learning models for flood susceptibility prediction mapping in the Middle Ganga Plain, India.

This study is an attempt to quantitatively test and compare novel advanced-machine learning algorithms in terms of their performance in achieving the goal of predicting flood susceptible areas in a low altitudinal range, sub-tropical floodplain environmental setting, like that prevailing in the Middle Ganga Plain (MGP), India. This part of the Ganga floodplain region, which under the influence of undergoing active tectonic regime related subsidence, is the hotbed of annual flood disaster. This makes the region one of the best natural laboratories to test the flood susceptibility models for establishing a universalization of such models in low relief highly flood prone areas. Based on highly sophisticated flood inventory archived for this region, and 12 flood conditioning factors viz. annual rainfall, soil type, stream density, distance from stream, distance from road, Topographic Wetness Index (TWI), altitude, slope aspect, slope, curvature, land use/land cover, and geomorphology, an advanced novel hybrid model Adaptive Neuro Fuzzy Inference System (ANFIS), and three metaheuristic models-based ensembles with ANFIS namely ANFIS-GA (Genetic Algorithm), ANFIS-DE (Differential Evolution), and ANFIS-PSO (Particle Swarm Optimization), have been applied for zonation of the flood susceptible areas. The flood inventory dataset, prepared by collected flood samples, were apportioned into 70:30 classes to prepare training and validation datasets. One independent validation method, the Area-Under Receiver Operating Characteristic (AUROC) Curve, and other 11 cut-off-dependent model evaluation metrices have helped to conclude that the ANIFS-GA has outperformed other three models with highest success rate AUC = 0.922 and prediction rate AUC = 0.924. The accuracy was also found to be highest for ANFIS-GA during training (0.886) & validation (0.883). Better performance of ANIFS-GA than the individual models as well as some ensemble models suggests and warrants further study in this topoclimatic environment using other classes of susceptibility models. This will further help establishing a benchmark model with capability of highest accuracy and sensitivity performance in the similar topographic and climatic setting taking assumption of the quality of input parameters as constant.

Adherence to guidelines for hormonal evaluation in patients with incidentally detected adrenal nodules: effects of radiology report wording and standardized reporting.

OBJECTIVE: To compare the rates of hormonal evaluation in patients who had CT reports describing adrenal incidentalomas with and without a specific recommendation for hormonal evaluation. MATERIALS AND METHODS: We performed a retrospective review of adult outpatients without a history of cancer who had a CT report describing an incidental adrenal nodule. Radiology reports were reviewed to determine whether a standardized macro was used which gave specific recommendations for hormonal evaluation and endocrinology consultation. If no macro was used it was determined whether the report had a recommendation for hormonal evaluation and endocrinology consultation. RESULTS: A standardized macro recommending hormonal evaluation and endocrinology referral was used in 45/129 (34.8%) reports that described an incidental adrenal nodule. A recommendation for hormonal evaluation was made in 5/84 (6.0%) reports without a macro. Hormonal evaluation was performed in 24/50 (48.0%) patients whose reports recommended it and in 11/79 (13.9%) patients whose reports did not (p < 0.0001). A recommendation for endocrinology referral was made in 2/84 (2.4%) reports without a macro. Patients were seen by endocrinology in 12/47 (25.5%) patients whose reports recommended an endocrinology referral evaluation and 5/82 (6.1%) patients whose reports did not (p < 0.0001). Hormonal evaluation was performed in 17/17 (100%) patients who were seen by endocrinology and 18/112 (16.1%) patients who were not (p < 0.0001). Eleven patients (8.5%) had an evaluation suggesting hyperfunctioning nodules (4 cortisol producing, 6 aldosterone producing, and 1 pheochromocytoma). CONCLUSIONS: Utilizing standardized macros that make specific recommendations for hormonal evaluation in patients with adrenal incidentalomas leads to improved adherence to clinical guidelines.

Geriatric Patients Carry Increased Risk for Deep Venous Thrombosis and Pulmonary Embolism in Reduction Mammaplasty: An Analysis of 1897 Geriatric Patients Among 25,909 Cases From 2005 to 2017 National Surgical Quality Improvement Project Databases.

INTRODUCTION: Reduction mammaplasty is one of the most common plastic surgery procedures performed. No study has evaluated whether geriatric patients are at greater risk for developing postoperative complications relative to nongeriatric patients. METHODS: The American College of Surgeons National Surgical Quality Improvement Project (NSQIP) database was reviewed for reduction mammaplasty procedures from 2005 to 2017. Hypothesis testing for demographics, comorbidities, and postoperative complications between geriatric and nongeriatric patients was performed. Statistically significant differences were then evaluated with multivariate logistic regression analysis. RESULTS: A total of 25,909 reduction mammaplasties were collected by NSQIP from 2005 to 2017, with 1897 patients older than 64 years (8% of all cases). The average age for geriatric breast reduction patients was 69 years versus 41.5 years for nongeriatric patients. Rates of comorbidities including diabetes, smoking status, dyspnea status, and hypertension medication were statistically different between the groups. Rates of deep venous thrombosis (DVT) and pulmonary embolism (PE) were significantly higher in geriatric versus nongeriatric patients, respectively (0.32 vs 0.06, P < 0.001 and 0.37 vs 0.09, P < 0.001). Multivariate analysis demonstrated geriatric patients had a 4.2 and 3.9 times higher risk of developing a DVT and PE than nongeriatric patients (C.I. 1.5-11.6, P = 0.006 and C.I. 1.6-9.8, P = 0.004). DISCUSSION: This study represents the largest evaluation of geriatric reduction mammaplasties in the United States. Although rare, geriatric age confers a 4 times increased risk for developing DVT and PE relative to nongeriatric patients all while adjusting for preoperative risk factors in reduction mammaplasty. Plastic surgeons should consider counseling their geriatric patients regarding these increased risks.

Tuberculous scleritis in a young Asian Indian girl-a case presentation and literature review.

Scleritis is the severe painful inflammation of the sclera, which can be infectious or non-infectious. Tuberculosis (TB) is one of the common causes of infectious scleritis. TB, though endemic in countries like India, is rare in pediatric age group. We report a case of a 9-year-old female child who presented with bilateral non-necrotizing anterior scleritis with unilateral posterior scleritis secondary to TB. To our knowledge, this is a rare presentation in pediatric age group, and she is the youngest of few cases of tuberculous posterior scleritis reported in literature.

Comparative analysis of shear bond strength of lithium disilicate samples cemented using different resin cement systems: An in vitro study.

AIM: This study aims to evaluate and compare the shear bond strength (SBS) of three different resin cements - total etch and rinse, self-etch and self-adhesive resin cements, used to bond the lithium disilicate restorations to human dentin. SETTINGS AND DESIGN: Comparative -Invitro study design. MATERIALS AND METHODS: Forty-five lithium disilicate (IPS E.max) discs (4 mm in diameter and 3 mm thick) were fabricated and randomly divided into three groups (n = 15). The occlusal surfaces of 45 extracted human maxillary premolars were ground flat. Fifteen specimens were luted, under a constant load, with each of the following resin cement: Variolink N (Group VN), Multilink N (Group MN), and Multilink Speed (Group MS). All cemented specimens were stored in distilled water for 1-week following which, they were tested under shear loading at a constant crosshead speed of 1 mm/min until fracture on a universal testing machine; the load at fracture was reported in megapascals (MPa) as the bond strength. Fractured specimens were also inspected by the scanning electron microscopy. Statistical analysis of the collected data was performed using one-way ANOVA test, post hoc Bonferroni test, and Chi-square test (α =0.05). STATISTICAL ANALYSIS USED: Oneway ANOVA test and post hoc Bonferroni test. RESULTS: Mean SBS data of the groups in MPa were: Variolink N (Group VN): 14.19 ± 0.76; Multilink N (Group MN): 10.702 ± 0.75; and Multilink Speed (Group MS): 5.462 ± 0.66. Significant differences in SBS (P < 0.001) of the three resin cement were found. Intergroup comparison revealed statistically significant differences in SBS between Groups VN and MN (P < 0.001), Groups B and C (P < 0.001), and Groups VN and MS (P < 0.001). Chi-square test used to compare the distribution of mode of bond failure among the three groups delineated that the cohesive failure was significantly more among Group VN, whereas adhesive failure was significantly more among Group MN and MS. CONCLUSION: Total etch and rinse resin cement, i.e., Variolink N (Group VN) produced significantly higher bond strength of all-ceramics to dentin surfaces than did the self-etch and self-adhesive resin cements, i.e., Multilink N and Multilink Speed, respectively.

Evaluation of the effect of implant angulations and impression techniques on implant cast accuracy - An in vitro study.

AIM: The purpose of this study was to evaluate the accuracy of implant casts generated with splinted and nonsplinted impression techniques with multiple parallel and nonparallel implants. MATERIALS AND METHODS: In this experimental study, two edentulous maxillary stainless steel models with seven implant analogs in the central incisor, canine, premolar, and first molar region simulating clinical condition were used (control groups). In one master model, implant analogs were placed parallel to each other, whereas in another model, analogs were placed with a tilt-to-longitudinal axis. Forty stone casts were made from each model using splined and nonsplinted technique using polyether with open-tray technique. Then, the difference in the distance between the master cast and experimental cast in three dimensions was measured by coordinate-measuring machine. One-way ANOVA, post hoc Bonferroni test, and unpaired t-test were used for data analysis. RESULTS: Statistical comparisons were made using ANOVA test, post hoc test, and unpaired t-test. Splinted technique with parallel implants generated interimplant distance values closest to the master model, followed by nonsplinted technique with parallel implants, splinted technique with angulated implants, and nonsplinted technique with angulated implants. CONCLUSIONS: Splinted impression technique exhibited higher accuracy than the other technique studies in both parallel and angulated implants.

Oral Health Behavior and Treatment Needs among Drug Addicts and Controls in Amritsar District: A Case-controlled Study.

BACKGROUND: Substance and drug abuse is associated with severe psychosocial problems, violence and health complications. AIMS: The aim of the study was to evaluate and compare the oral hygiene status and sugar eating patterns among drug addicts with their age, gender and socio-economic status matched controls. SETTINGS AND DESIGN: The present study comprised of two groups-Group A comprised of 100 drug addicts and Group B included 100 controls. The study sample were interviewed and subjected to a comprehensive intra-oral examination. METHODS AND MATERIAL: Standardized methods of evaluation were performed using mouth mirror, dental probe, explorer and WHO probe. STATISTICAL ANALYSIS: The data was subjected to statistical analysis using Chi Square test and student t-test. RESULTS AND CONCLUSIONS: CPITN index revealed bleeding in 56% addicts and calculus in 20% addicts. The mean DMFT of group A was 5.71 as compared to 2.45 in group B. The frequency of sugar consumption was found to be high in addicts as compared to the controls. Significant P values (< 0.001) of DMFT index, periodontal status and frequency of sugar consumption were obtained on statistical analysis. The caries status was found to be poor in addicts, but the periodontal treatment needs were similar for both group A and B. Oral health promotion should be undertaken in drug rehabilitation centers for overall success of withdrawl treatment.