Design of Promising Uranyl(VI) Complexes Thin Films with Potential Applications in Molecular Electronics.

In this work, it is proposed the development of organic semiconductors (OS) based on uranyl(VI) complexes. The above by means of the synthesis and the characterization of the complexes by Infrared spectroscopy, Nuclear magnetic resonance spectroscopy, mass spectrometry, and X-ray diffraction. Films of these complexes were deposited and subsequently, topographic and structural characterization was carried out by Scanning Electron Microscopy, X-ray diffraction, and Atomic Force Microscopy. Additionally, the nanomechanical evaluation was performed to know the stiffness of uranyl films using their modulus of elasticity. Also, the optical characterization took place in the devices and their bandgap value ranges between 2.40 and 2.93 eV being the minor for the film of the uranyl complex with the N on pyridine in position 4 (2 c). Finally, the electrical behavior of the uranyl(VI) films was evaluated, and important differences were obtained: the uranyl complex with the N on pyridine in position 2 (2 a) film is not influenced by changes in lighting and its current density is in the order of 10-3 A/cm2. The film with uranyl complex with the N on pyridine in position 3 (2 b) and 2 c presents a greater current flow under lighting conditions and two orders of magnitude larger than in film 2 a. In these films 2 b and 2 c, ohmic behavior occurs at low voltages, while at high voltages the charge transport changes to space-charge limited current behavior.

Aislamiento y elucidación estructural por resonancia magnética nuclear (RMN 1H, RMN 13C, DEPT135, COSY y HSQC) del compuesto (E)-1,3,5-trimetoxi-2-(prop-1-enil) benceno extraído de hojas de Piper patulum / Isolation and structural elucidation by nuclear magnetic resonance (1H NMR, 13C NMR, DEPT135, COSY and HSQC) of compound (E) -1,3,5-trimethoxy-2- (prop-1-enyl) benzene extracted from Piper patulum

Guatemala es un país de gran diversidad biológica, la que ha permitido a diferentes investigadores de productos naturales, obtener resultados de interés y relevancia científica, principalmente sobre propiedades farmacológicas, sin embargo, hasta el momento se desconoce la estructura molecular, conformaciones y configuraciones exactas de muchos de los metabolitos secundarios responsables de dichas propiedades. Por lo tanto, en esta investigación se planteó como objetivo aislar y elucidar la estructura de un fenilpropanoide obtenido en las hojas de Piper patulum. El aislamiento se realizó por extracciones líquido-líquido y técnicas cromatográficas (cromatografía en columna -CC-), obteniendo .092 g del compuesto de interés. La elucidación se realizó por espectroscopía de masas, espectroscopia infrarroja -IR- y experimentos de resonancia magnética nuclear -RMN-, dando como resultado la estructura correspondiente a (E)-1,3,5-trimetoxi-2-(prop-1- enil) benceno. Posteriormente el fenilpropanoide presentó actividad antioxidante mediante la prueba cualitativa con 2,2- difenil-1-picrilhidrazilo -DPPH-.

Guatemala is a country of great biological diversity, which has led natural product researchers to obtain results of great interest and scientific relevance, mainly in pharmacological properties; However, the molecular structure, conformations, and configurations of many secondary metabolites responsible for these properties are unknown. In this research, the objective was to isolate and elucidate the structure of a phenylpropanoid obtained from in the leaves of Piper patulum. The isolation was carried out by liquid-liquid extractions and chromatographic techniques (Column Chromatography -CC-), obtaining .092 g. The elucidation was performed by mass spectroscopy, infrared spectroscopy -IR- and nuclear magnetic resonance experiments-NMR-, the data obtained indicates the corresponding (E) -1,3,5-trimethoxy-2- (prop-1-enyl) benzene. Subsequently, the phenylpropanoid presented antioxidant activity through the qualitative test with 2,2-diphenyl-1-picrylhydrazyl-DPPH

Isolated aortic dilation without osteoarthritis: a case of SMAD3 mutation.

Aneurysm-osteoarthritis syndrome is a recently discovered inherited autosomal dominant connective tissue disease caused by SMAD3 mutations. Aneurysm-osteoarthritis syndrome is responsible for 2% of familial thoracic aortic aneurysms and dissections and is characterised by aneurysms, dissections, and tortuosity throughout the arterial tree in combination with osteoarthritis. Early-onset osteoarthritis is present in almost all patients. We present the case of a non-syndromic young boy with SMAD3 mutation isolated from the dilated aortic root and ascending aorta without osteoarthritis.

Flora etnoodontológica de las comunidades indígenas embera del Atrato Medio antioqueño / Ethno-dentistry flora of the embera indigenous communities from Antioquia’s Medio Atrato region

Introducción: entre los espacios de uso y manejo de la sucesión de bosque hecho por los embera que habitan ecosistemas húmedos tropicales del Chocó biogeográfico se encuentran una serie de plantas de uso odontológico. Métodos: para ello se partióde técnicas de investigación etnográfica que se complementaron con registro fotográfico, toma de muestras botánicas, formatos, notas de campo e identificación taxonómica. Resultados: este trabajo muestra a manera de inventario la composición florística yalgunos apuntes etnobotánicos acerca de las especies identificadas y reconocidas por las comunidades indígenas del Atrato Medio que presentan un valor medicinal cultural en la salud oral de este grupo étnico; entre los que se destacan cinco especies, tres géneros de diferentes formas de crecimiento y dos familias, las cuales son usadas en prevención bucal. Conclusiones: este trabajo pudoconstatar, a manera de conclusión, cómo este tipo de prácticas odontológicas, como un conocimiento ancestral asociado a ellas, se viene perdiendo especialmente entre la gente joven e incluso adulta de estas etnias.

Introduction: the forest areas traditionally used and managed by the embera native communities living in thebiogeographic Chocó’s tropical rainforests ecosystems contain several plants of dental use. Methods: this study used ethnographic research approaches supported by photographs, botanical samples, forms, field work notes, and taxonomic identification. Results:in the form of an inventory, this work presents the floristic composition and some ethno-botanic notes on the species identified and recognized by the native communities from the Medio Atrato river region which have a medical/cultural value for the oral health of this ethnic group; five species are especially important: three genera of different growing patterns and two families, which are used in preventive oral health. Conclusions: this study allowed concluding that the aforementioned dental practices, and the ancestral knowledge connected to them, are being gradually forgotten, especially by young people but even by the adult membersof these ethnic groups.

Detection and Identification of a Group 16SrIII-Related Phytoplasma Associated with Coffee Crispiness Disease in Colombia.

Coffee crispiness ("crespera"), a disease of uncertain etiology, has been endemic in coffee (Coffea arabica L.) plantations in Colombia for at least 60 years. Symptoms typically consist of bud proliferation, abundant short and narrow leaves, phyllody, floral abortion, monospermic fruit, and dwarfing of plants. In severe cases, coffee crispiness disease (CCD) can affect production significantly. In this study, association of a phytoplasma with CCD was indicated by the accumulation of Diene's stain, or 4', 6-diamidino-2-phenylindole fluorescence, only in phloem of affected plant tissues. The presence of polymorphic phytoplasma cells in phloem sieve tube elements was confirmed by transmission electron microscopy. The disease was transmitted successfully by grafting symptomatic shoots from CCD-affected C. arabica plants onto young, healthy rootstocks; however, symptoms failed to develop after mechanical inoculation of young plants with extracts derived from diseased plant tissues. A nested polymerase chain reaction (PCR) assay employing primer pairs P1/P7 followed by FU5/rU3 amplified a 16S ribosomal DNA product (941 bp) exclusively from DNA of diseased plants. Sequence and phylogenetic analysis of the nested PCR product identified the CCD phytoplasma as a new strain member of group 16SrIII (X-disease group). This is the first report of a phytoplasma infecting coffee plants.

Low-level laser-assisted liposuction: the Neira 4 L technique.

Low-level laser-assisted liposuction (LLLL), known as the Neira 4 L technique, is an excellent adjuvant tool for the surgeon practicing liposculpture. A low-level laser is used to create a transitory pore in the cell membrane of the adipocyte to move fat from inside the cell to the interstitial space outside without killing the cell. LLLL has been performed successfully in in-vitro and human adipose tissue cultures. It protects the patient from the surgical trauma of liposuction by protecting and preparing tissues for the surgical trauma; modulating the inflammatory response to prevent short and long-term side effects of surgery; and improving the quality and quantity of the healing process by accelerating recovery time, modulating secondary cicatrization, and preventing postoperative neuralgias.

Fat liquefaction: effect of low-level laser energy on adipose tissue.

Low-level laser energy has been increasingly used in the treatment of a broad range of conditions and has improved wound healing, reduced edema, and relieved pain of various etiologies. This study examined whether 635-nm low-level lasers had an effect on adipose tissue in vivo and the procedural implementation of lipoplasty/liposuction techniques. The experiment investigated the effect of 635-nm, 10-mW diode laser radiation with exclusive energy dispersing optics. Total energy values of 1.2 J/cm(2), 2.4 J/cm(2), and 3.6 J/cm(2) were applied on human adipose tissue taken from lipectomy samples of 12 healthy women. The tissue samples were irradiated for 0, 2, 4, and 6 minutes with and without tumescent solution and were studied using the protocols of transmission electron microscopy and scanning electron microscopy. Nonirradiated tissue samples were taken for reference. More than 180 images were recorded and professionally evaluated. All microscopic results showed that without laser exposure the normal adipose tissue appeared as a grape-shaped node. After 4 minutes of laser exposure, 80 percent of the fat was released from the adipose cells; at 6 minutes of laser exposure, 99 percent of the fat was released from the adipocyte. The released fat was collected in the interstitial space. Transmission electron microscopic images of the adipose tissue taken at x60,000 showed a transitory pore and complete deflation of the adipocytes. The low-level laser energy affected the adipose cell by causing a transitory pore in the cell membrane to open, which permitted the fat content to go from inside to outside the cell. The cells in the interstitial space and the capillaries remained intact. Low-level laser-assisted lipoplasty has a significant impact on the procedural implementation of lipoplasty techniques.