1.
J Org Chem
; 81(15): 6867-74, 2016 08 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27387595
RESUMO
Addition of diarylphosphine oxides to the NâN double bond of azobenzenes leads to the formation of the P-substituted hydrazines in up to 98% yield for 24 examples, and the formation of diphenylphosphinic amides was observed in three substrates. This strategy features tolerance of a wide range of functional groups, simple operation, and mild reaction conditions. Specially, this method can be also applied to the gram-scale synthesis of the product. A polar reaction mechanism is also proposed based on control experiments.