[Biochemical, structural and biomechanical features of human scleral matrix in primary open-angle glaucoma].

The goal of the investigation was to study the changes of scleral matrix collagen in progressing primary open-angle glaucoma (POAG). In scleral samples of 16 patients aged 52-81 years with different stages of POAG amino acid composition, collagen content and cross-linking ratio characterizing tissue rigidity were estimated. Collagen I was found to be the dominant type in sclera of glaucomatous and normal eyes, though as POAG progressing the content and cross-linking increase, that underlies the scleral rigidity increase and permeability decrease. Similar ratio of collagen cross-linking with age and glaucoma progression give evidence of specific pathologic changes of the dominant matrix component, that may be one of significant pathogenic factor of POAG.

[Sensitivity of different tissues of rats to the effects of a permanent magnetic field]. / O chuvstvitel'nosti razlichnykh tkanei krys k vozdeistviiu postoiannogo magnitnogo polia.

The biological effects of magnetic fields are known to be realized through the water structure of living organisms, which is the 60-90% of cells. In this respect the experiments investigating the magnetosensitivity of different tissues of rats by measuring the changes of hydration are of great interest. As it was shown, the tissues with higher hydration state (brain) were more sensitive to SMF influence, where depending on the exposure time the hydration of brain tissue increased. The hydration of the liver tissue, which was initially the least, was not changed.