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Clin Exp Dermatol ; 35(4): 388-91, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19874314

RESUMO

BACKGROUND: Injection of botulinum toxin into certain areas of face that carry a high risk of ptosis (danger zone) needs caution in application. An example is the lateral forehead, particularly the lower portion. AIM: In this study, we evaluated the efficacy and safety of treating supraciliary wrinkles in the lower lateral forehead by injections of botulinum toxin at the temporal hairline, keeping a reasonable distance from danger zone. METHODS: In this randomized clinical trial, 40 women (mean age 35 years) were selected and divided into two groups, A and B. both groups were treated with botulinum toxin to treat wrinkles in the frown area, as well as frontal lines and lateral canthus lines. Group B received extra injections at each temporal line for treatment of supraciliary wrinkles. RESULTS: There was a significant difference in total wrinkle number and mean number of wrinkles between the two groups after injections (paired t-test, P < 0.01). No ptosis was seen in either group. CONCLUSIONS: Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective.


Assuntos
Toxinas Botulínicas Tipo A/farmacologia , Fármacos Neuromusculares/farmacologia , Envelhecimento da Pele/efeitos dos fármacos , Adulto , Toxinas Botulínicas Tipo A/administração & dosagem , Toxinas Botulínicas Tipo A/efeitos adversos , Método Duplo-Cego , Feminino , Testa/patologia , Humanos , Injeções Intramusculares , Fármacos Neuromusculares/administração & dosagem , Fármacos Neuromusculares/efeitos adversos
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