[Possible changes in the electroencephalogram and electrocardiogram after the introduction of peripheral muscle relaxants]. / Vozmozhnye izmeneniya elektroentsefalogrammy i elektrokardiogrammy pri ispol'zovanii miorelaksantov perifericheskogo deistviya.

OBJECTIVE: To evaluate the changes in the electroencephalogram (EEG) parameters in time, coinciding with the changes recorded by the electrocardiogram (ECG) channel in patients after the introduction of peripheral muscle relaxants. MATERIAL AND METHODS: Twenty-four patients were examined in intensive care units on artificial lung ventilation (ALV). During the study, myographic artifacts were recorded in all patients in the EEG, the elimination of which was impossible without the use of pharmacological agents leading to relaxation of muscles - muscle relaxants of peripheral action. RESULTS: Complete suppression of myographic artifacts on the EEG was noted in all patients after the introduction of peripheral muscle relaxants. However, in 4 of them, EEG changes were noted in the period 2 to 3 minutes after the introduction of muscle relaxants and the disappearance of myographic artifacts on the EEG. These changes coincided in time with the changes recorded by the ECG channel. CONCLUSIONS: The EEG changes in time, coinciding with the changes in ECG indicators, suggest the presence of short-term disturbances of the functional state of the basic brain systems, probably due to changes in hemodynamics due to cardiac rhythm and conduction disturbances. It is advisable to record the EEG with the inclusion of an ECG channel in the wiring diagram for synchronous recording.

[The changes in electroencephalogram parameters in patients in the somatogenic phase of acute poisoning with opioid receptor agonists]. / Izmeneniya pokazatelei elektroentsefalogrammy u patsientov v somatogennuyu fazu ostrykh otravlenii agonistami opioidnykh retseptorov.

OBJECTIVE: To evaluate the parameters of the electroencephalogram (EEG) using the methods of computer processing of EEG data for an approach to the analysis of possible neurophysiological mechanisms underlying the fluctuations detected in the EEG in patients in the somatogenic phase of acute poisoning with opioid receptor agonists. MATERIAL AND METHODS: Thirty-one patients were examined in the somatogenic phase of acute poisoning with opioid receptor agonists with a wakefulness level 3 to 15 points on the Glasgow Coma Scale. The EEG was recorded in accordance with the recommendations of the International Federation of Clinical Neurophysiology. The indicators of electrical activity of the brain were analyzed; computer processing of EEG data, including spectral analysis, localization of equivalent dipole sources of pathological electrical activity of the brain localization of the maximum of the equivalent density of EEG oscillation currents in the neocortex, was performed. RESULTS: Delta-band oscillations dominated in the majority of patients (65%, 20 patients). EEG delta waves were localized mainly at the level of the thalamus; using the method of low-resolution electromagnetic tomography, the localization of the maximum of the equivalent current density of delta oscillations in the projection of the neocortex was noted. Possible neurophysiological mechanisms of «pathological¼ delta waves recorded in the EEG of these patients are discussed. CONCLUSIONS: The changes on the EEG in these patients arise as a result of a disturbance of the function of the generator mechanisms of both cortical and activating structures of the brain, while the recorded slow-wave, mainly delta activity, taking into account the recording time (somatogenic phase), may be due to the action of secondary alternating factors (hypoxia and cerebral edema).