A Review on Small Organic Colorimetric and Fluorescent Hosts for the Detection of Cobalt and Nickel Ion.

In recent years, there has been a notable increase in efforts to advance efficient hosts for detecting cobalt and nickel ions, driven by their extensive industrial applications and environmental significance. This review meticulously examines the progress made in small organic colorimetric and fluorescent hosts tailored specifically for the sensitive and selective detection of cobalt and nickel ions. It delves into a diverse range of molecular architectures, including organic ligands, elucidating their unique attributes such as sensitivity, selectivity, and response time. Moreover, the review precisely explores the underlying principles governing the colorimetric and fluorescent mechanisms employed by these hosts, shedding light on the intricate interactions between the sensing moieties and the target metal ions. Furthermore, it critically evaluates the practical applicability of these hosts, considering crucial factors such as detection limits, recyclability, and compatibility with complex sample matrices. Additionally, exploration extends to potential challenges and prospects in the field, emphasizing the imperative for ongoing innovation to address emerging environmental and analytical demands. Eventually, through this comprehensive examination, the review seeks to contribute to the ongoing endeavor to develop robust and efficient tools for monitoring and detecting cobalt and nickel metal ions in diverse analytical scenarios.

Synthesis of CuO, ZnO nanoparticles, and CuO-ZnO nanocomposite for enhanced photocatalytic degradation of Rhodamine B: a comparative study.

Water pollution, arising from the presence of toxic dyes and chemicals, is a global challenge, urging the need for eco-friendly solutions in water decontamination. This study focused on the synthesis of copper oxide nanoparticles (CuO NPs), zinc oxide nanoparticles (ZnO NPs), and a bimetallic CuO-ZnO nanocomposite (CZ NC) through an environmentally friendly method employing Tragia involucrata L. leaf extract. Comprehensive analysis of structural and optical properties involved using various analytical techniques such as XRD, FT-IR, XPS, UV-DRS, PL, FE-SEM, EDAX, TEM, SAED, zeta potential, TGA, and BET. In comparison to pristine CuO and ZnO NPs, the CZ-NC demonstrated notably enhanced photocatalytic activity in the degradation of Rhodamine B dye (RhB). The optimum conditions for RhB degradation were found to be a pH of 9 and a catalyst dosage of 1 mg/mL for a concentration of 10 ppm. Under these conditions, CuO NPs, ZnO NPs, and CZ-NC demonstrated high efficiencies of 78%, 83%, and 96.1% respectively over 105 min. Through LC-HRMS, the identification of degradation products offered valuable insights into the pathway of photocatalytic degradation. Furthermore, toxicity analysis of intermediates, conducted through ECOSAR software, indicated the formation of non-toxic by-products (ChV/LC50/EC50 > 100) after the completion of the reaction. Furthermore, the recycled catalysts exhibited sustained stability for up to 4 cycles, with only a minor decrease in activity of up to 6.8%. This confirms their catalytic efficacy in purifying polluted water. This research significantly contributes to the progress of environmentally friendly nanocomposites, enhancing their efficacy in the realm of environmental remediation.

Sunlight-assisted photocatalytic degradation of orange G dye using cost-effective zinc oxide nanoparticles.

We have used an environmentally friendly approach to produce zinc oxide nanoparticles from an aqueous extract of Cucumis maderaspatanus L. leaves (Cm-ZnO NPs). Leaf extract phytoconstituents work as both reducing and stabilising agents. Calcination at 300, 500, 700, and 800 °C allowed fine-tuning of the bandgap of synthesised Cm-ZnO NPs, which has been well-characterized. The XRD analysis confirmed the crystalline nature of the Cm-ZnO NPs. The Cm-ZnO NPs were found to be spherical and averaged 8.6 nm in size, as determined by transmission electron microscopy and field emission scanning electron microscopy. TGA testing validated the nanoparticles' resilience to heat. The zeta potential measurements showed that the Cm-ZnO NPs were stable. By analysing the sorption of nitrogen onto the nanoparticles, we were able to calculate their surface area, which came in at 19 m2/g. The degradation of orange G (OG) dye in the presence of hydrogen peroxide (H2O2) served as an oxidizing agent and measured the photocatalytic efficiency of the Cm-ZnO NPs. In addition, the effect of varying dye, H2O2, and catalyst concentrations on photodegradation was studied. The rate of reactions was computed. In conclusion, the obtained data demonstrated that the produced Cm-ZnO NPs can be employed as a cost-efficient catalyst for textile industrial effluent treatment.

Development and Validation of a LC-MS/MS Method for the Profiling of Impurities Formed during Stress Study of Antifungal Agent-Efinaconazole.

Liquid chromatography interfaced with mass spectroscopy (LC-MS) is a sensitive and effective analytical method that combines high-resolution separation as well as specific mass detection of impurities in formulated products and as well as in active pharmaceutical ingredient (API). In this study, LC-MS/MS was used to determine impurities formed during the stability period of Efinaconazole (EFZ, a triazole antifungal agent). The method was validated for its assay parameters such as specificity, linearity, accuracy, precision and also for solution stability. The calibration curve was found to be linear for the concentration range from 0.5 µg/mL to 30 µg/mL. A thorough investigation was performed by exposing Efinaconazole (1 mg/mL) to various stress conditions such as hydrolysis (acid and alkaline), oxidation, photolysis and temperature at various time intervals to achieve 10% degradation. The impurities formed during forced degradation were separated using high-performance liquid chromatography later it was identified using LC-MS/MS technique. The obtained results showed that EFZ is prone to oxidation when exposed to a 3% aqueous medium of hydrogen peroxide solution and quite stable in all the remaining stress conditions for a longer period.