Relationship of zinc level with pathogenetically significant homeostasis disorders in severely burned patients.

The aim of the study was to assess the zinc content and identify the relationship between the concentration of this element and changes in the biochemical status of patients and markers of inflammation during burn shock. We examined 23 patients aged 45.3±16.1 years with burns of I-II-III degree, area of 31-80%. The serum concentrations of zinc, albumin, interleukin-6, C-reactive protein (CRP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined. The majority of patients (21/23) had severe hypocincemia, correlated with burn area (r=-0.53; p=0.008). A decrease in zinc levels during burn shock was associated with the development of hypoalbuminemia (r=0.52, p=0.01). The association of deviations in ALT and AST activity with changes in zinc concentration was revealed (-0.59<γ<-0.61, 0.008

[Clinical immunological peculiarities of complicated course of odontogenic phlegmons of maxillofacial region].

Based upon clinical immunological checkup of 76 patients with common phlegmons of maxillofacial region, their complications and analysis of general phlogogenic activity the variants of hyperergic inflammation process flow were determined, that allowed to diagnose its activity and forecast possibility of its further development and its outcome.

[Automated micromethod in the assessment of lysozyme activity]. / Avtomatizirovannyi mikrometod opredeleniia lizotsimnoi aktivnosti.

An automated micromethod for assessment of the lysozyme activity in the blood serum and saliva using a special program is presented. The test is carried out in 96-well polystyrene plates, this helping to save the reagents and spare the test samples without making the assessment less sensitive. The method intensifies the process of measurement, which is particularly evident in prophylactic screening for the detection of groups at risk of body reactivity reduction, local immunity disorders in children and adults, this latter fact being especially valuable.