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1.
Phys Eng Sci Med ; 45(1): 83-96, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34822131

RESUMO

This study presents a method with high accuracy performance that aims to automatically detect schizophrenia (SZ) from electroencephalography (EEG) records. Unlike related literature studies using traditional machine learning algorithms, the features required for the training of the network are automatically extracted from the EEG records in our method. In order to obtain the time frequency features of the EEG signals, the signal was converted into 2D by using the Continuous Wavelet Transform method. This study has the highest accuracy performance in the relevant literature by using 2D time frequency features in automatic detection of SZ disease. It is trained with Visual Geometry Group-16 (VGG16), an advanced convolutional neural networks (CNN) deep learning network architecture, to extract key features found on scalogram images and train the network. The study shows a high success in classifying SZ patients and healthy individuals with a very satisfactory accuracy of 98% and 99.5%, respectively, using two different datasets consisting of individuals from different age groups. Using different techniques [Activization Maximization, Saliency Map, and Gradient-weighted Class Activation Mapping (Grad-CAM)] to visualize the learning outcomes of the CNN network, the relationship of frequency components between SZ and the healthy individual is clearly shown. Moreover, with these interpretable outcomes, the difference between SZ patients and healthy individuals can be distinguished very easily help for expert opinion.


Assuntos
Aprendizado Profundo , Esquizofrenia , Eletroencefalografia/métodos , Humanos , Aprendizado de Máquina , Redes Neurais de Computação , Esquizofrenia/diagnóstico por imagem
2.
Phys Eng Sci Med ; 44(4): 1201-1212, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34505992

RESUMO

Migraine is one of the major neurovascular diseases that recur, can persist for a long time, cripple or weaken the brain. This study uses electroencephalogram (EEG) signals for the diagnosis of migraine, and a computer-aided diagnosis system is presented to support expert opinion. A tunable Q-factor wavelet transform (TQWT) based method is proposed for the analysis of the oscillatory structure of EEG signals. With TQWT, EEG signals are decomposed into sub bands. Then, the features are statistically calculated from these bands. The success of the obtained features in distinguishing between migraine patients and healthy control subjects was performed using the Kruskal Wallis test. Feature values ​​obtained from each sub band were classified using well-known ensemble learning techniques and their classification performances were tested. Among the evaluated classifiers, the highest classification performance was achieved as 89.6% by using the Rotation Forest algorithm with the features obtained with Sub band 2. These results reveal the potential of the study as a tool that will support expert opinion in the diagnosis of migraine.


Assuntos
Transtornos de Enxaqueca , Análise de Ondaletas , Algoritmos , Eletroencefalografia , Humanos , Aprendizado de Máquina , Transtornos de Enxaqueca/diagnóstico
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