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Prog Biophys Mol Biol ; 140: 124-132, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29776659

RESUMO

The response of adult Wistar albino female rats toward two dose rates of gamma radiation delivered as acute dose of 7 Gy is investigated using classical methodologies as chemical, hematological and histological parameters in comparison with newly introduced dielectric parameters. Two groups of rats were exposed to γ ray with dose rates 533.35 mGy/min and 325.89 mGy/min. Then the irradiated groups were followed up for two weeks after irradiation. In case of higher dose rate, high percentage of animals was lost and there were substantial alterations in the dielectric parameters in addition to massive damage in liver and bone marrow cells. On the other hand, a reduction of death rate of rats, different behavior in the dielectric parameters of bone marrow and lesser injury of liver tissue were well noticeable in case of lower dose rate. Moreover, the sensitivity of dielectric parameters toward the two different dose rates was well pronounced during the 1st and 2nd weeks after irradiation more than other parameters.


Assuntos
Medula Óssea/efeitos da radiação , Doses de Radiação , Animais , Relação Dose-Resposta à Radiação , Impedância Elétrica , Feminino , Raios gama/efeitos adversos , Testes Hematológicos , Fígado/imunologia , Fígado/efeitos da radiação , Ratos , Ratos Wistar
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