A severe laryngeal angioedema reaction from cefadroxil in a patient with no known allergies to penicillins.

We report a life-threatening anaphylactic reaction to cefadroxil in a 60-year old female with no previous history of allergies to penicillins. Cefadroxil is a first-generation cephalosporin and anaphylactic reactions to it in patients with no previous history of penicillin allergy are very rare. Since cefadroxil is a commonly prescribed antibiotic for both adults and children in the Caribbean, an appropriate level of caution should be exercised in its use even with no reported history of previous allergies to the penicillin class of medications.

Dapsone syndrome: A case study.

A 47-year-old woman developed fever, dermatitis, lymphadenopathy and hepatitis a few days after taking dapsone. She was investigated and diagnosed as'dapsone syndrome'

The hypereosinophilic syndrome.

A 64-year old woman patient with dry pruritic rash, oral ulcers, persistent cough and significant weight loss was investigated and proved to be a case of hypereosinophilic syndrome.

Generalized umbilicated granuloma annulare.

Generalised umbilicated granuloma annulare is reported in an elderly man. There was no association of diabetes or other systemic disease.

Wells' syndrome.

Eosinophilic cellulitis/Wells' syndrome is a rare dermatosis with erythematous, urticarial plaques that become more indurated and eventually have grey blue discoloration. The histopathology is distinctive, with a diffuse infiltrate composed predominantly of eosinophils but admixed with lymphocytes, histicytes and occasionally multinucleated histiocytes. There is dermal edema with so called "flame figures" that is composed of collagen focally enveloped with aggregates of eosinophilic granules. These collagen fibres may be surrounded by palisading histiocyes. The course is variable with waxing and waning and eventual spontaneous resolution.

Glucagonoma syndrome.

A case of glucagonoma is being presented. The patient presented with erosions, crusts, bullous dermatitis, glucose intolerance and weight loss.

Follicular mucinosis.

A case of follicular mucinosis is being reported. Clinically, the patient had discrete follicular and non-follicular papules on the face, neck and arms. Light microscopy confirmed the follicular outer root sheath, and sebaceous gland epithelial degenerative changes. The infiltrating inflammatory cells were morphologically benign. The response to oral dapsone therapy is highlighted.