Late occurrence of malignancy following resection of a histologically mature sacrococcygeal teratoma. Report of a case and literature review.

A sacrococcygeal adenocarcinoma is reported in a male patient nearly 40 years old following resection of a histologically mature sacrococcygeal teratoma. The adenocarcinoma arose within soft tissue of the presacral area and residual coccyx and extensively invaded the coccygeal stump that had not been removed in toto with the teratoma during initial surgery at 2 months of age. The patient died nearly 2 years later with local and regional recurrence of tumor and metastases to lymph nodes, liver, lung, bone, and brain. At autopsy there was no evidence of origin from deep internal organs such as the stomach, pancreas, or other sites. Brief comments are made about malignant tumors complicating sacrococcygeal teratomas in both the pediatric age group and adults, and attention is focused on other lesions entering into the differential diagnosis, particularly retrorectal cyst/hamartoma or tailgut cysts. This case underscores an extremely rare but potentially fatal outcome of a patient with sacrococcygeal teratoma.

Apheresis in a community hospital: six years' experience.

We present our six-year experience with apheresis in a community hospital in northern Virginia. A total of 2,892 procedures were done, including 2,232 thrombocytaphereses on normal donors for collection of platelets and 660 therapeutic plasma exchanges in patients having a variety of disorders. We hope our experience will be helpful to those who contemplate setting up similar programs.