Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 16 de 16
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
PLoS One ; 18(8): e0289690, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37549129

RESUMO

In an increasingly interconnected society, preventing epidemics has become a major challenge. Numerous infectious diseases spread between individuals by a vector, creating bipartite networks of infection with the characteristics of complex networks. In the case of dengue, a mosquito-borne disease, these infection networks include a vector-the Aedes aegypti mosquito-which has expanded its endemic area due to climate change. In this scenario, innovative approaches are essential to help public agents in the fight against the disease. Using an agent-based model, we investigated the network morphology of a dengue endemic region considering four different serotypes and a small population. The degree, betweenness, and closeness distributions are evaluated for the bipartite networks, considering the interactions up to the second order for each serotype. We observed scale-free features and heavy tails in the degree distribution and betweenness and quantified the decay of the degree distribution with a q-Gaussian fit function. The simulation results indicate that the spread of dengue is primarily driven by human-to-human and human-to-mosquito interaction, reinforcing the importance of controlling the vector to prevent episodes of epidemic outbreaks.


Assuntos
Aedes , Vírus da Dengue , Dengue , Animais , Humanos , Dengue/epidemiologia , Dengue/prevenção & controle , Mosquitos Vetores , Surtos de Doenças , Simulação por Computador
2.
PLoS One ; 16(3): e0248708, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33735290

RESUMO

COVID-19 pandemic is an immediate major public health concern. The search for the understanding of the disease spreading made scientists around the world turn their attention to epidemiological studies. An interesting approach in epidemiological modeling nowadays is to use agent-based models, which allow to consider a heterogeneous population and to evaluate the role of superspreaders in this population. In this work, we implemented an agent-based model using probabilistic cellular automata to simulate SIR (Susceptible-Infected-Recovered) dynamics using COVID-19 infection parameters. Differently to the usual studies, we did not define the superspreaders individuals a priori, we only left the agents to execute a random walk along the sites. When two or more agents share the same site, there is a probability to spread the infection if one of them is infected. To evaluate the spreading, we built the transmission network and measured the degree distribution, betweenness, and closeness centrality. The results displayed for different levels of mobility restriction show that the degree reduces as the mobility reduces, but there is an increase of betweenness and closeness for some network nodes. We identified the superspreaders at the end of the simulation, showing the emerging behavior of the model since these individuals were not initially defined. Simulations also showed that the superspreaders are responsible for most of the infection propagation and the impact of personal protective equipment in the spreading of the infection. We believe that this study can bring important insights for the analysis of the disease dynamics and the role of superspreaders, contributing to the understanding of how to manage mobility during a highly infectious pandemic as COVID-19.


Assuntos
COVID-19/epidemiologia , Análise de Sistemas , COVID-19/prevenção & controle , COVID-19/transmissão , Controle de Doenças Transmissíveis , Simulação por Computador , Humanos , Pandemias , Equipamento de Proteção Individual , Probabilidade , SARS-CoV-2/isolamento & purificação
3.
Sci Rep ; 10(1): 13339, 2020 08 07.
Artigo em Inglês | MEDLINE | ID: mdl-32769988

RESUMO

Modern society is increasingly massively connected, reflecting an omnipresent tendency to organize social, economic, and technological structures in complex networks. Recently, with the advent of the so-called multiplex networks, new concepts and tools were necessary to better understand the characteristics of this type of system, as well as to analyze and quantify its performance and efficiency. The concept of diversity in multiplex networks is a striking example of this intrinsically interdisciplinary effort to better understand the nature of complex networks. In this work, we introduce the Multiplex Efficiency Index, which allows quantifying the temporal evolution of connectivity diversity, particularly when the number of layers of the multiplex network varies over time. Using data related to air passenger transportation in Brazil we investigate, through the new index, how the Brazilian air transportation network has being changing over the years due to the privatization processes of airports and mergers of airlines in Brazil. Besides that, we show how the Multiplex Efficiency Index is able to quantify fluctuations in network efficiency in a non-biased way, limiting its values between 0 and 1, taking into account the number of layers in the multiplex structure. We believe that the proposed index is of great value for the evaluation of the performance of any multiplex network, and to analyze, in a quantitative way, its temporal evolution independently of the variation in the number of layers.

4.
Phys Rev E ; 101(5-1): 052138, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32575275

RESUMO

We study the Ising model on the square lattice (Z^{2}) and show, via numerical simulation, that allowing interactions between spins separated by distances 1 and m (two ranges), the critical temperature, T_{c}(m), converges monotonically to the critical temperature of the Ising model on Z^{4} as m→∞. Only interactions between spins located in directions parallel to each coordinate axis are considered. We also simulated the model with interactions between spins at distances of 1, m, and u (three ranges), with u a multiple of m; in this case our results indicate that T_{c}(m,u) converges to the critical temperature of the model on Z^{6}. For percolation, analogous results were proven for the critical probability p_{c} [B. N. B. de Lima, R. P. Sanchis, and R. W. C. Silva, Stochast. Process. Appl. 121, 2043 (2011)STOPB70304-414910.1016/j.spa.2011.05.009].

5.
Phys Rev E ; 101(4-1): 042123, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32422776

RESUMO

Understanding the topological characteristics of complex networks and how they affect navigability is one of the most important goals in science today, as it plays a central role in various economic, biological, ecological, and social systems. Here we apply first-passage analysis tools to investigate the properties and characteristics of random walkers in networks with different topology. Starting with the simplest two-dimensional square lattice, we modify its topology incrementally by randomly reconnecting links between sites. We characterize these networks by first-passage time from a significant number of random walkers without interaction, varying the departure and arrival locations. We also apply the concept of first-passage simultaneity, which measures the likelihood of two walkers reaching their destination together. These measures, together with the site occupancy statistics during the processes, allowed us to differentiate the studied networks, especially the random networks from the scale-free networks, by their navigability. We also show that small-world features can also be highlighted with the proposed technique.

6.
Phys Rev E ; 96(3-1): 032305, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29346931

RESUMO

We propose a stock market model which is investigated in the forms of difference and differential equations whose variables correspond to the demand or supply of each agent and to the price. In the model, agents are driven by the behavior of their trust contact network as well by fundamental analysis. By means of the deterministic version of the model, the connection between such drive mechanisms and the price is analyzed: imitation behavior promotes market instability, finitude of resources is associated to stock index stability, and high sensitivity to the fair price provokes price oscillations. Long-range correlations in the price temporal series and heavy-tailed distribution of returns are observed for the version of the model which considers different proposals for stochasticity of microeconomic and macroeconomic origins.

7.
Biosystems ; 150: 22-34, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27501921

RESUMO

An advanced vision of the mRNA translation is presented through a hybrid modeling approach. The dynamics of the polysome formation was investigated by computer simulation that combined agent-based model and fine-grained Markov chain representation of the chemical kinetics. This approach allowed for the investigation of the polysome dynamics under non-steady-state and non-continuum conditions. The model is validated by the quantitative comparison of the simulation results and Luciferase protein production in cell-free system, as well as by testing of the hypothesis regarding the two possible mechanisms of the Edeine antibiotic. Calculation of the Hurst exponent demonstrated a relationship between the microscopic properties of amino acid elongation and the fractal dimension of the translation duration time series. The temporal properties of the amino acid elongation have indicated an anti-persistent behavior under low mRNA occupancy and evinced the appearance of long range interactions within the mRNA-ribosome system for high ribosome density. The dynamic and temporal characteristics of the polysomal system presented here can have a direct impact on the studies of the co-translation protein folding and provide a validated platform for cell-free system studies.


Assuntos
Simulação por Computador , Modelos Biológicos , Polirribossomos/fisiologia , Biossíntese de Proteínas/fisiologia , Animais , Sistema Livre de Células/fisiologia , Humanos , RNA Mensageiro/biossíntese , RNA Mensageiro/genética
8.
Artigo em Inglês | MEDLINE | ID: mdl-26066183

RESUMO

We present a probabilistic cellular automaton (PCA) model to study solid-on-solid interface growth in which the transition rules depend on the local morphology of the profile obtained from the interface representation of the PCA. We show that the model is able to reproduce a wide range of patterns whose critical roughening exponents are associated to different universality classes, including random deposition, Edwards-Wilkinson, and Kardar-Parisi-Zhang. By means of the growth exponent method, we consider a particular set of the model parameters to build the two-dimensional phase diagram corresponding to a planar cut of the higher dimensional parameter space. A strong indication of phase transition between different universality classes can be observed, evincing different regimes of deposition, from layer-by-layer to Volmer-Weber and Stransk-Krastanov-like modes. We expect that this model can be useful to predict the morphological properties of interfaces obtained at different surface deposition problems, since it allows us to simulate several experimental situations by setting the values of the specific transition probabilities in a very simple and direct way.

9.
Eur Phys J E Soft Matter ; 35(5): 38, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22623037

RESUMO

We report new segregation phenomena in the clogging arches formed during the discharge of granular piles. Results from molecular dynamics simulations show segregation effects with respect to both size and density ratios used in piles built with bidisperse mixtures of grains. The clogging arch is preferentially constituted of large grains when size bidisperse piles were discharged, whereas for density bidisperse mixtures there is a predominance of light grains in the arch for large orifice widths but, for small widths, an inversion in the preference is observed, with a slightly higher incidence of heavy grains forming the arches. We present arguments based on the reverse buoyancy effect and the statistics collected for the avalanche size distributions to explain how these effects can be understood as a crossover between two different segregation mechanisms acting independently at small and large orifice width limits.

10.
Phys Rev E Stat Nonlin Soft Matter Phys ; 82(5 Pt 1): 051303, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21230469

RESUMO

We present a molecular-dynamics study of discharges in a granular pile evincing a catastrophic regime depending on the outlet size. The avalanche size distribution function suggests a phase transition where the height of the remaining pile is taken as the order parameter. Our results indicate that there is a critical outlet size beyond which discharges become catastrophic and the initial pile is split in two minor piles. As the system size increases, finite-size analysis indicates that the critical orifice width converges to a finite value.

11.
Phys Rev Lett ; 99(6): 068001, 2007 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-17930866

RESUMO

In this Letter we report spontaneous pattern formation in dense granular assemblies confined to a Hele-Shaw cell and quasistatic regime. Varied unexpected patterns, ranging from rounded to fingered, are observed due to the displacement of one granular material by another. Computer simulations reproduce the major features observed in these experiments. Two mechanisms are responsible for the pattern formation: crystallization of the injected grains and plastic deformation of the displaced grains. The experiment suggests analogies with viscous fingering and jamming transition experiments.


Assuntos
Carbono/química , Ácido Láctico/química , Modelos Teóricos , Ácido Poliglicólico/química , Polímeros/química , Poliestirenos/química , Aço/química , Materiais Biocompatíveis/química , Simulação por Computador , Copolímero de Ácido Poliláctico e Ácido Poliglicólico
12.
Phys Rev Lett ; 96(16): 168001, 2006 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-16712277

RESUMO

It is demonstrated, by numerical simulations of a 2D assembly of polydisperse disks, that there exists a range (plateau) of coarse-graining scales for which the stress tensor field in a granular solid is nearly resolution independent, thereby enabling an "objective" definition of this field. Expectedly, it is not the mere size of the system but the (related) magnitudes of the gradients that determine the widths of the plateaus. Ensemble averaging (even over "small" ensembles) extends the widths of the plateaus to subparticle scales. The fluctuations within the ensemble are studied as well. Both the response to homogeneous forcing and to an external compressive localized load (and gravity) are studied. Implications to small solid systems and constitutive relations are briefly discussed.


Assuntos
Algoritmos , Simulação por Computador , Porosidade , Estresse Mecânico
13.
Eur Phys J E Soft Matter ; 17(1): 93-100, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15864732

RESUMO

We relate the pressure "dip" observed at the bottom of a sand pile prepared by successive avalanches to the stress profile obtained on sheared granular layers in response to a localized vertical overload. We show that, within a simple anisotropic elastic analysis, the skewness and the tilt of the response profile caused by shearing provide a qualitative agreement with the sand pile dip effect. We conclude that the texture anisotropy produced by the avalanches is in essence similar to that induced by a simple shearing --albeit tilted by the angle of repose of the pile. This work also shows that this response function technique could be very well adapted to probe the texture of static granular packing.

14.
Phys Rev E Stat Nonlin Soft Matter Phys ; 67(1 Pt 2): 016107, 2003 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-12636564

RESUMO

We study a (1+1)-dimensional probabilistic cellular automaton that is closely related to the Domany-Kinzel stochastic-cellular automaton (DKCA), but in which the update of a given site depends on the state of three sites at the previous time step. Thus, compared with the DKCA, there is an additional parameter p(3) representing the probability for a site to be active at time t, given that it and its nearest neighbors were active at time t-1. We study phase transitions and critical behavior for the activity and for damage spreading, using one- and two-site mean-field approximations, and simulations, for p(3)=0 and p(3)=1. We find evidence for a line of tricritical points in the (p(1),p(2),p(3)) parameter space, obtained using a mean-field approximation at pair level. To construct the phase diagram in simulations we employ the growth-exponent method in an interface representation. For p(3)=0, the phase diagram is similar to the DKCA, but the damage-spreading transition exhibits a reentrant phase. For p(3)=1, the growth-exponent method reproduces the two absorbing states, first- and second-order phase transitions, bicritical point, and damage-spreading transition recently identified by Bagnoli et al. [Phys. Rev. E 63, 046116 (2001)].

15.
Phys Rev E Stat Nonlin Soft Matter Phys ; 66(4 Pt 2): 046135, 2002 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12443287

RESUMO

We construct the quasistationary (QS) probability distribution for the Domany-Kinzel stochastic cellular automaton (DKCA), a discrete-time Markov process with an absorbing state. QS distributions are derived at both the one-and two-site levels. We characterize the distributions by their mean, and various moment ratios, and analyze the lifetime of the QS state, and the relaxation time to attain this state. Of particular interest are the scaling properties of the QS state along the critical line separating the active and absorbing phases. These exhibit a high degree of similarity to the contact process and the Malthus-Verhulst process (the closest continuous-time analogs of the DKCA), which extends to the scaling form of the QS distribution.

16.
Phys Rev E Stat Nonlin Soft Matter Phys ; 66(1 Pt 2): 016113, 2002 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12241432

RESUMO

The critical behavior at the frozen-active transition in the Domany-Kinzel stochastic cellular automaton is studied via a surface growth process in (1+1) dimensions. At criticality, this process presents a kinetic roughening transition; we measure the critical exponents in simulations. Two update schemes are considered: in the symmetric scheme, the growth surfaces belong to the directed percolation (DP) universality class, except at one terminal point. At this point, the phase transition is discontinuous and the surfaces belong to the compact directed percolation universality class. The relabeling of space-time points in the nonsymmetric scheme alters significantly the surface growth, changing the values of the critical exponents. The critical behavior of rough surfaces at the nonchaotic-chaotic transition is also studied using the damage spreading technique; the exponents confirm DP values for the symmetric scheme.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...