RESUMO
Ninety-two cases of granular corneal dystrophy, most of them belonging to 5 pedigrees are described. The age of manifestation in this Finnish type of granular dystrophy is first in the end of the second decade, and visual acuity is in mean normal through the whole life. An autopsy study showed no changes outside cornea elsewhere in the eyeball. In one family with granular dystrophy, another type of dystrophy, hereditary fleck dystrophy of the cornea, was accidentally found.
Assuntos
Distrofias Hereditárias da Córnea/genética , Adulto , Idoso , Arco Senil/genética , Arco Senil/patologia , Córnea/inervação , Córnea/patologia , Distrofias Hereditárias da Córnea/patologia , Cristalinas , Feminino , Finlândia , Humanos , Masculino , Pessoa de Meia-Idade , Sistema Nervoso/patologia , Linhagem , Acuidade VisualRESUMO
A follow-up study including examinations made by a paediatrician, an ophthalmologist and a psychologist and complemented with EEG-recordings and a number of laboratory determinations was performed at the age of 3 years on 41 children who had received phototherapy during the first week of life and on 42 control children of the same age. No differences were found in growth, development, social maturity, neurological or ophthalmologic disorders, EEG-recordings or laboratory determinations between both groups. It seems unlikely that phototherapy causes any harmful longterm effects provided that the eyes are shielded.
