[Treatment of chlamydia infections and a brief review of the problems]. / Liecba chlamýdiových infekcií a strucný prehl'ad problematiky.

The authors treated 35 patients (17 males, 18 females) with chlamydial infection of the urogenital system by means of azithromycin dosed 1.0 g for the first day, 500 mg from the second till the fifth day of treatment with 82.9% effectivity.

Generalized melanosis with malignant melanoma metastasizing to skin--a pathological study with S-100 protein and HMB-45.

A patient with primary malignant melanoma localized to the right gluteal region is described. Four years later and after intercurrent influenza, disseminated metastases of malignant melanoma to the skin occurred. After a further 6 months melanodermia developed and lasted until the death of the patient (6 months later). Autopsy revealed melanosis of the visceral organs. Histology taken from internal organs using S-100 protein and HMB-45 melanoma methods confirmed metastases of malignant melanoma to the skin, oral cavity, palatal tonsils, nasal and nasopharyngeal mucosae, lungs, myocardium and brain. The authors discuss the mechanism of melanosis--a rare sign in patients with metastasizing malignant melanoma.