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1.
Clin Case Rep ; 10(6): e5962, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35734192

RESUMO

In the absence of typical features and risks for life-threatening chest pain including aortic dissection, the obligation and urgency for their evaluation remains unimpeachable, more so when patients present in stable conditions suggestive of benign etiology. Better do the painstaking, rather than be undone by the pain.

2.
BMJ Case Rep ; 15(2)2022 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-35131788

RESUMO

Familial hypokalaemic periodic paralysis (FHPP) is a rare neuromuscular disorder that is classified under periodic paralysis (PP), which is characterised by episodes of muscle weakness. Common triggers include intense exercise, fasting or consumption of carbohydrate-rich meals. Hypokalaemic PP has an incidence of 1 in 100 000; despite the temporal association, cardiac manifestations are exceedingly rare. We present a case of FHPP, a channelopathy presenting with severe refractory hypokalaemia. The challenges with our patient were maintaining potassium levels within normal ranges and initiating a close follow-up plan. Due to the lack of clinical guidance in our case, many aspects of care, including surveillance, medications and genetic testing, remain unaddressed. Medical management includes aggressive correction with supplements, potassium-sparing diuretics and carbonic anhydrase inhibitors. Severe cases of dysrhythmias, especially ventricular fibrillation, require electrophysiology evaluation and possible implantation of a defibrillator to prevent sudden cardiac death.


Assuntos
Hipopotassemia , Paralisia Periódica Hipopotassêmica , Inibidores da Anidrase Carbônica , Testes Genéticos , Humanos , Hipopotassemia/etiologia , Paralisia Periódica Hipopotassêmica/diagnóstico , Paralisia Periódica Hipopotassêmica/tratamento farmacológico , Paralisia Periódica Hipopotassêmica/etiologia , Paralisia , Potássio
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