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Int J Gynecol Cancer ; 15(2): 366-71, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15823127

RESUMO

Cervical cancer during pregnancy is rare, occurring in approximately 3% of cervical cancer cases. Considerable controversy exists as to the long-term prognosis of patients diagnosed during pregnancy. A 32-year-old female presented with vaginal spotting in April 1998. A prenatal smear in December 1996 revealed atypical glandular cells of undetermined significance. A sterile speculum exam in April 1997 at 31-week gestational age revealed a polyp on the anterior lip of the cervix, pathology consistent with a well-differentiated villoglandular adenocarcinoma. In August 1997, the patient underwent a radical hysterectomy with pelvic/para-aortic lymphadenectomy. In April 2001, she represented with nodular perineal mass in the episiotomy incision. She received preoperative radiotherapy with a near-complete response and remained without disease for >10 months. It appears that a less radical procedure can offer significant therapeutic value. Preoperative radiotherapy proved effective at achieving a near-complete response. The patient underwent a wide local excision of the perineal area with resultant negative margins.


Assuntos
Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Episiotomia/efeitos adversos , Recidiva Local de Neoplasia , Complicações Neoplásicas na Gravidez/patologia , Neoplasias do Colo do Útero/patologia , Neoplasias do Colo do Útero/cirurgia , Adenocarcinoma/radioterapia , Adulto , Feminino , Humanos , Terapia Neoadjuvante , Períneo/patologia , Períneo/cirurgia , Gravidez , Neoplasias do Colo do Útero/radioterapia
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