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1.
Nat Prod Res ; 18(5): 465-71, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15248616

RESUMO

Two new isoflavones 1 and 2 along with eleven known compounds 3-13, have been isolated for the first time from the rhizomes of Iris soforana. The structures of these compounds were determined on the basis of spectroscopic methods and found to be 5,3'-dihydroxy-4'-methoxy-6,7-methylenedioxyisoflavone (1) (Soforanarin A), and 5,7,5'-trimethoxy-6,3',4'-trihydroxyisoflavone (2) (Soforanarin B).


Assuntos
Iris , Isoflavonas/química , Fitoterapia , Extratos Vegetais/química , Humanos , Espectroscopia de Ressonância Magnética , Raízes de Plantas
2.
Phytother Res ; 17(5): 575-7, 2003 May.
Artigo em Inglês | MEDLINE | ID: mdl-12749005

RESUMO

In vitro biological activities including bactericidal, fungicidal and insecticidal activities as well as phytotoxicity and brine shrimp toxicity of the petroleum ether, chloroform and ethyl acetate extracts of Iris germanica L. were determined. The bactericidal activity of the extracts was assayed by the agar well diffusion test. In the fungicidal test, the agar tube dilution method was used. The insecticidal activity was determined by the exposure method. The toxicity of the extracts was evaluated by the phytotoxicity test as well as the brine shrimp toxicity test. The chloroform and ethyl acetate extracts of I. germanica rhizomes exhibited bactericidal activity, while the petroleum ether extract did not exhibit any bactericidal, fungicidal and insecticidal activities. It was also inactive in the brine shrimp toxicity test, whereas it showed significant phytotoxicity against the plant Lemna aequinoctialis Welv. Two known isoflavones were isolated from the chloroform extract of the plant.


Assuntos
Bactérias/efeitos dos fármacos , Benzopiranos/farmacologia , Dioxóis/farmacologia , Fungos/efeitos dos fármacos , Gênero Iris , Isoflavonas/farmacologia , Rizoma/química , Animais , Antibacterianos/farmacologia , Antifúngicos/farmacologia , Araceae/efeitos dos fármacos , Artemia/efeitos dos fármacos , Benzopiranos/química , Benzopiranos/isolamento & purificação , Dioxóis/química , Dioxóis/isolamento & purificação , Relação Dose-Resposta a Droga , Herbicidas/farmacologia , Insetos/efeitos dos fármacos , Inseticidas/farmacologia , Isoflavonas/química , Isoflavonas/isolamento & purificação , Estrutura Molecular , Extratos Vegetais/farmacologia , Testes de Toxicidade
3.
Fitoterapia ; 73(4): 316-9, 2002 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12234575

RESUMO

A new monocyclic triterpene ester (1) was isolated from the rhizomes of Iris germanica from Turkey. Structure elucidation of compound (1) was carried out by the combined application of HMQC, HMBC, DEPT, COSY and NOESY experiments and named as iristectorone K.


Assuntos
Iridaceae , Fitoterapia , Extratos Vegetais/química , Triterpenos/química , Humanos , Espectroscopia de Ressonância Magnética , Raízes de Plantas , Turquia
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