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1.
Adv Exp Med Biol ; 1237: 75-95, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31302869

RESUMO

Cellular-based therapies have drawn a great deal of attention thanks to their regenerative medicine approaches to treat incurable diseases and specific injuries. In this regard, injectable cell delivery systems could actualize the therapeutically beneficial outcomes of cell-based therapeutic products. These systems have found considerable clinical uses. Hence, the recent studies have focused on developing injectable bio-constructs to protect transplanted cells during delivery and stimulating endogenous regeneration through interactions of these cells and host tissue. This paper introduces a framework, as a general concept, to improve cell delivery systems for cell-based therapeutic products. Studies on stable injectable carriers can enhance cell homing, proliferation, viability, dressing of irregular shape of target sites, and subsequently support transplanted cell functionality. However, more studies should be conducted on new technologies for the injectable cell-based product for cell delivery and the clinical applications.


Assuntos
Terapia Baseada em Transplante de Células e Tecidos/tendências , Medicina Regenerativa/tendências , Qualidade de Produtos para o Consumidor , Humanos
2.
Glob J Health Sci ; 8(10): 55248, 2016 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-27302439

RESUMO

INTRODUCTION: In all human societies, domestic violence is known as a threat. Violence is imposing one's will on others through mental pressure and physical damage then can cause a feeling of anxiety and insecurity in them, especially for the weaker and more vulnerable groups such as women, children, elderly and minority groups who are the victims of oppression and socioeconomic inequalities. According to statistics, Ardabil, in comparison with other Iran's provinces, has the most number of violent crimes. This qualitative research was conducted with the aim of exploring pathological phenomena of social violence in Ardabil province. METHODS: this qualitative study was conducted with expert panel. Eighteen participants were selected with targeted sampling method from professors and the heads of the administrative offices who were linked to the phenomenon of social violence and have rich experiences with the social violence issues. After obtaining an informed consent from the participants, expert panel were conducted in two sessions of 150 minutes. At each session all discourse was recorded and after that, immediately transcribed verbatim. Then, the codes, sub-themes and the themes were obtained. RESULTS: The five main extracted themes included: social, historical and anthropological, cultural, economic and regional factors and 13 sub-themes were classified. CONCLUSION: Social, economic, cultural and regional structure, which have been formed and institutionalized in the society over the years, can be influenced and changed by government policies and a variety of programs.

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