RESUMO
BACKGROUND: Risk-reducing operations are an important part of the management of hereditary predisposition to cancer. In selected cases, they can considerably reduce the morbidity and mortality associated with cancer in this population. OBJECTIVES: The Brazilian Society of Surgical Oncology (BSSO) developed this guideline to establish national benchmarks for cancer risk-reducing operations. METHODS: The guideline was prepared from May to December 2021 by a multidisciplinary team of experts to discuss the surgical management of cancer predisposition syndromes. Fourteen questions were defined and assigned to expert groups that reviewed the literature and drafted preliminary recommendations. Following a review by the coordinators and a second review by all participants, the groups made final adjustments, classified the level of evidence, and voted on the recommendations. RESULTS: For all questions including risk-reduction bilateral salpingo-oophorectomy, hysterectomy, and mastectomy, major agreement was achieved by the participants, always using accessible alternatives. CONCLUSION: This and its accompanying article represent the first guideline in cancer risk reduction surgery developed by the BSSO, and it should serve as an important reference for the management of families with cancer predisposition.
Assuntos
Neoplasias da Mama , Ginecologia , Neoplasias Ovarianas , Oncologia Cirúrgica , Brasil/epidemiologia , Neoplasias da Mama/genética , Neoplasias da Mama/prevenção & controle , Neoplasias da Mama/cirurgia , Feminino , Humanos , Mastectomia , Neoplasias Ovarianas/cirurgiaRESUMO
Racional - A maioria dos tumores hepáticos benignos são achados incidentais durante a ultra-sonografia abdominal. As formas mais encontradas são: hemangioma, hiperplasia nodular focal, e adenoma. Objetivo - Descrever quatro casos de pacientes portadores de tumores hepáticos benignos. Casuística e Métodos - Quatro pacientes portadores de doença hepática benigna foram submetidos a ressecção hepática, sendo um do sexo masculino e três do sexo feminino. Relacionaram-se no estudo: abordagem diagnóstica, modalidade cirúrgica, extensão da ressecção, perda sanguínea, sexo, histologia tumoral e complicaçõespós-operatória...