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Orv Hetil ; 149(19): 889-92, 2008 May 11.
Artigo em Húngaro | MEDLINE | ID: mdl-18450549

RESUMO

UNLABELLED: The treatment of chronic hepatitis caused by hepatitis C virus (HCV) has got now success only in 40-60 per cent of cases with combined interferon and ribavirin therapy. In patients infected by HCV not only the liver but other organs can have alterations. The treatment should be generally applied in a one-year period, and its administration should be carefully carried out both by the patients and the doctors. It can be accompanied by several complications. Beside these the other diseases of the patient's organs can have some problems. AIM OF THE STUDY: The demonstration of a patient history with clinical success who had hypertension and renal disease. CASE REPORT: 42-year-old female patient who had hypertension and kidney diseases in her anamnesis. Her complaints started with mild abdominal symptoms in 2000. The biochemical alterations and the positive reaction with HCV-PCR test showed HCV infection. Its genotype was 1b. The patient tolerated the combined peginterferon-alfa-2a and ribavirin treatment well, between August 2006 and August 2007. She became HCV-PCR negative after six-month treatment and also at the end of therapy. DISCUSSION: The concomitant diseases of the patient made the treatment heavier, but not impossible. CONCLUSION: The elimination of HCV infection can be possible also in the case of hypertension and decreased renal function.


Assuntos
Antivirais/uso terapêutico , Hepatite C/tratamento farmacológico , Hipertensão/complicações , Interferon-alfa/uso terapêutico , Polietilenoglicóis/uso terapêutico , Insuficiência Renal Crônica/complicações , Ribavirina/uso terapêutico , Adulto , Quimioterapia Combinada , Feminino , Hepacivirus/efeitos dos fármacos , Hepacivirus/isolamento & purificação , Hepatite C/complicações , Humanos , Hipertensão/fisiopatologia , Interferon alfa-2 , Reação em Cadeia da Polimerase , Proteínas Recombinantes , Insuficiência Renal Crônica/fisiopatologia , Resultado do Tratamento
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