RESUMO
Mycoplasma hominis is a common colonizer of the lower genitourinary tract. Although its clinical relevance for causing urogenital infections in immunocompetent individuals is controversial, this bacterium has been involved in severe invasive infections in allograft recipients. In this report, we describe two cases of M. hominis infection in two young renal transplant recipients within the first month post-transplant. Although at first no epidemiological link between the two cases had been suspected, whole-genome sequencing (WGS) analysis showed that both isolates were identical, highly suggestive of an origin with the common organ donor.
Assuntos
Transplante de Rim/efeitos adversos , Infecções por Mycoplasma/microbiologia , Mycoplasma hominis/genética , Transplantados , Sequenciamento Completo do Genoma , Adulto , Antibacterianos/uso terapêutico , Etilenoglicóis/intoxicação , Humanos , Masculino , Nefrite Intersticial/complicações , Insuficiência Renal/etiologia , Insuficiência Renal/cirurgia , Doadores de Tecidos , Adulto JovemRESUMO
A 46-year-old immunosuppressed patient presented with a breast implant-associated infection 10 years after breast augmentation in Southeast Asia. No pathogen was identified in the initial conventional microbiological workup. Subsequently, infection with Mycobacterium abscessus-a nontuberculous mycobacteria-was diagnosed using a special culture technique. Increased rates of such infections are reported after cosmetic surgery in foreign countries, presumably due to inoculation with these ubiquitous pathogens. This case highlights the fact that the differential diagnosis and thus the microbiological workup should be extended in cases without initial pathogen detection.
Assuntos
Implantes de Mama/efeitos adversos , Corpos Estranhos/microbiologia , Mastodinia/etiologia , Infecções por Mycobacterium não Tuberculosas/diagnóstico , Micobactérias não Tuberculosas/isolamento & purificação , Infecções Relacionadas à Prótese/microbiologia , Infecção da Ferida Cirúrgica/microbiologia , Implantes de Mama/microbiologia , Febre/etiologia , Humanos , Hospedeiro Imunocomprometido , Pessoa de Meia-Idade , Infecções por Mycobacterium não Tuberculosas/microbiologiaRESUMO
A patient with acute myeloid leukemia developed disseminated tuberculosis with cerebral involvement in the early phase of induction chemotherapy before allogenic stem cell transplantation. He presented with persisting fever of unknown origin, and initially misinterpreted organ lesions in CT scans.
