1.
Clin Infect Dis
; 49(7): 1080-2, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19712035
RESUMO
Moxifloxacin cerebrospinal fluid (CSF) penetration was evaluated by obtaining full plasma and CSF time concentration curves for 4 patients with tuberculous meningitis. The geometric mean ratio of the areas under the curve for CSF to plasma were 0.82 (range, 0.70-0.94) at 400 mg once per day and 0.71 (0.58-0.84) at 800 mg once per day.