Intracerebral hemorrhage in methanol toxicity patients during COVID-19 pandemic: case report and review of literature.

PURPOSE: The aim of this study is to examine the clinical and imaging manifestations of methanol toxicity during the COVID-19 pandemic, as well as to review existing studies on this topic. The most common cause of methanol intoxication is methanol-adulterated liquor. The primary metabolite of methanol, formic acid, is responsible for pathological changes. Symptoms typically present within 6-24 h of consumption and can include visual disturbances, acute neurological symptoms, and gastrointestinal issues. During the initial year of the COVID-19 pandemic, methanol poisoning cases increased significantly. METHODS: In this study, We present six different patients with methanol intoxication and their clinical and imaging features. RESULTS: In the literature review, the most common clinical presentation was loss of consciousness and obtundation and the other was vision loss. CT scan findings showed bilateral putaminal necrosis and hemorrhage in 55% of methanol toxicity patients. CONCLUSION: Methanol intoxication, causing bilateral putaminal involvement and a 50% mortality rate in intracerebral hemorrhage patients, warrants urgent toxicological analysis due to potential putaminal hemorrhage.

Brown-Séquard syndrome caused by multiple knife trauma gunshot with late debridement: Two cases report and literature review.

INTRODUCTION AND IMPORTANCE: Brown-Séquard syndrome (BSS) is a rare syndrome consequence of interruption in the spinal cord following traumatic or non-traumatic injuries. Although, based on the previous literature, BSS has a good prognosis, some reports do not complete recovery following BSS. CASES PRESENTATION: In this current survey, we present two aggressive BSSs with complete recovery. One case involved a man aged 23 years without any underlying disease with multiple traumas with a knife who was transferred to the level 1 trauma center knife. Case two was a man 36 years with a gun shutting in C6 level. CLINICAL DISCUSSION: C5 total laminectomy and C4 and C6 partial laminectomy were done due to the sharp knife. Three months later, the patient achieved full recovery. After C6 total laminectomy in case 2, the patient was discharged without defect. CONCLUSION: Incomplete spinal cord injuries are challenging to diagnose and treat. Due to esophageal rupture and late debridement, full recovery was not expected. Despite neurological impairments, full recovery was achieved over three months in two cases. Also, many factors can aggravate the initial trauma in gunshot spine injury patients.

Trigeminal Neuralgia Caused by Venous Angioma: A Case Report and Review of the Literature.

BACKGROUND: Trigeminal neuralgia typically occurs in the middle-aged to elderly population, is believed to be related to abnormal conduction within the trigeminal nerve, and is possibly is attributable to changes in myelin induced by pulsatile mechanical trauma from an adjacent vessel. At the point just before it enters the brainstem, there is a short segment at which nerve axons are still ensheathed in central myelin (produced by oligodendrocytes), but after a few millimeters, there is a transition to peripheral myelin (produced by Schwann cells). The region of this transition is called the Obersteiner-Redlich zone. It is thought that the area of the nerve containing the central form of myelin is especially susceptible to pathologic changes from vascular contact that result in demyelination and altered conduction. When associated with a venous angioma at the root entry zone, trigeminal neuralgia usually presents at a younger age. METHODS: We report a 34-year-old man with a complaint of left hemifacial stabbing pain in maxillomandibular area that was triggered by chewing and speaking. On examination, no neurologic deficit was detected. The pain was not relieved significantly, even with the administration of carbamazepine. Magnetic resonance imaging demonstrated venous angioma in the left cerebello-pontine region. RESULTS: Microvascular decompression was performed uneventfully. The patient's pain was completely relieved without neurologic deficits. CONCLUSION: It seems that the trigeminal neuralgia caused by venous angioma may occur in the younger population. In most cases, the vessel that caused compression can be identified with magnetic resonance imaging without the need for intensive conventional angiography.