RESUMO
Carbofuran is a carbamate that functions as a cholinesterase inhibitor. Accidental or intentional ingestion can produce a life-threatening syndrome that requires prompt diagnosis and treatment. We describe a case of intentional carbofuran ingestion that resulted in coma, respiratory failure from acute respiratory distress syndrome (ARDS), and cortical blindness.
Assuntos
Carbofurano/intoxicação , Inseticidas/intoxicação , Tentativa de Suicídio , Adulto , Cegueira/induzido quimicamente , Inibidores da Colinesterase/intoxicação , Coma/induzido quimicamente , Humanos , Masculino , Doenças do Sistema Nervoso/induzido quimicamente , Síndrome do Desconforto Respiratório/induzido quimicamenteRESUMO
We describe a patient who had severe neurologic symptoms, psychiatric abnormalities, and secondary amenorrhea superimposed on a history of hemolytic anemia and micronodular cirrhosis attributed to hemochromatosis. The correct diagnosis of Wilson's disease was delayed until the appearance of Kayser-Fleischer rings and a low serum ceruloplasmin level. Appropriate treatment ameliorated symptoms, and maintenance therapy has been effective in retarding progression. It is essential to consider Wilson's disease in patients with unexplained hepatic, neurologic, and psychiatric dysfunction, because appropriate early medical treatment can prevent further organ damage and reduce the risk of permanent damage to the liver and brain.
