[Effect of serotonin on chromatin protein methylation in radiation injury]. / Vliianie serotonina na metilirovanie belkov khromatina pri luchevom porazhenii.

The paper deals with the influence of the X-irradiation and serotonin, as a radioprotector, on the chromatin protein methylation. It is shown that the X-irradiation and serotonin cause changes in the intensity of chromatin protein methylation in vivo, that may be explained by their effect on the activity of the corresponding methylases. Possible relationships between the changes in methylation of chromatin proteins and the general response of the organism to the irradiation, including administration of the radioprotector is under discussion.

[Adenylate cyclase system and structural modifications of nuclear proteins in organisms radioprotection]. / Adenilattsiklaznaia sistema i strukturnye modifikatsii iadernykh belkov pri zashchite organizma radioprotektorami ot luckevogo porazheniia.

The paper deals with modern ideas of ways and mechanisms for realization of the radioprotector antiradiation effect. The data on the effect of biogenic amines (serotonin in particular) and radiation on the cAMP system are analyzed. It is shown that one of the most important mechanisms of the radioprotective effect is realized by changing the levels of histones and nonhistone proteins modifications through the adenylate cyclase system which leads to regulation of the chromatin template activity.