RESUMO
Thyroid hormone level may be altered in chronic renal failure patients. Low levels of thyroxine protect the body from excess protein loss by minimizing catabolism. Hyperthyroidism is rarely encountered in end-stage dialysis dependent patients. Less than 10 well-documented cases of Graves' disease (GD) are reported in literature so far. We report a case of GD in a patient on dialysis.
RESUMO
Several 5-substituted alkoxy 20(S)-camptothecin analogues having A- and B-ring substituents were prepared via semi-synthesis. Most of these compounds were found to exhibit potent anti-cancer activity based on their in vitro cytotoxicity data obtained against human tumor cell lines.
Assuntos
Antineoplásicos Fitogênicos/síntese química , Antineoplásicos Fitogênicos/farmacologia , Camptotecina/síntese química , Camptotecina/farmacologia , Camptotecina/análogos & derivados , Relação Dose-Resposta a Droga , Humanos , Relação Estrutura-Atividade , Células Tumorais Cultivadas/efeitos dos fármacosRESUMO
Mania following or associated with medical and pharmacological conditions is well known. However there are no reports of mania in a case of acute viral hepatitis B infection. This paper describes a manic disorder in a young female with acute viral hepatitis B infection, without any past or family history of psychiatric illness or associated psychosocial stressors.
