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1.
J Vis Exp ; (145)2019 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-30882778

RESUMO

The mechanical response of a material under dynamic load is typically different than its behavior under static conditions; therefore, the common quasistatic equipment and procedures used for material characterization are not applicable for materials under dynamic loads. The dynamic response of a material depends on its deformation rate and is broadly categorized into high (i.e., greater than 200/s), intermediate (i.e., 10-200/s) and low strain rate regimes (i.e., below 10/s). Each of these regimes calls for specific facilities and testing protocols to ensure the reliability of the acquired data. Due to the limited access to high-speed servo-hydraulic facilities and validated testing protocols, there is a noticeable gap in the results at the intermediate strain rate. The current manuscript presents a validated protocol for the characterization of different materials at these intermediate strain rates. Strain gauge instrumentation and digital image correlation protocols are also included as complimentary modules to extract the utmost level of detailed data from every single test. Examples of raw data, obtained from a variety of materials and test setups (e.g., tensile and shear) is presented and the analysis procedure used to process the output data is described. Finally, the challenges of dynamic characterization using the current protocol, along with the limitations of the facility and methods of overcoming potential problems are discussed.


Assuntos
Processamento de Imagem Assistida por Computador , Teste de Materiais , Estresse Mecânico , Reprodutibilidade dos Testes
2.
J Biomech Eng ; 133(5): 051006, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21599097

RESUMO

Osseointegrated transfemoral implants have been introduced as a prosthetic solution for above knee amputees. They have shown great promise, providing an alternative for individuals who could not be accommodated by conventional, socket-based prostheses; however, the occurrence of device failures is of concern. In an effort to improve the strength and longevity of the device, a new design has been proposed. This study investigates the mechanical behavior of the new taper-based assembly in comparison to the current hex-based connection for osseointegrated transfemoral implant systems. This was done to better understand the behavior of components under loading, in order to optimize the assembly specifications and improve the useful life of the system. Digital image correlation was used to measure surface strains on two assemblies during static loading in bending. This provided a means to measure deformation over the entire sample and identify critical locations as the assembly was subjected to a series of loading conditions. It provided a means to determine the effects of tightening specifications and connection geometry on the material response and mechanical behavior of the assemblies. Both osseoinegrated assemblies exhibited improved strength and mechanical performance when tightened to a level beyond the current specified tightening torque of 12 N m. This was shown by decreased strain concentration values and improved distribution of tensile strain. Increased tightening torque provides an improved connection between components regardless of design, leading to increased torque retention, decreased peak tensile strain values, and a more gradual, primarily compressive distribution of strains throughout the assembly.


Assuntos
Simulação por Computador , Imageamento Tridimensional/métodos , Osseointegração , Ajuste de Prótese/instrumentação , Amputação Cirúrgica/reabilitação , Amputados/reabilitação , Análise de Variância , Membros Artificiais , Engenharia Biomédica , Força Compressiva , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Próteses e Implantes , Entorses e Distensões , Estresse Mecânico , Resistência à Tração , Torque , Suporte de Carga
3.
ACS Appl Mater Interfaces ; 3(5): 1441-50, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21495713

RESUMO

Multicomponent nanocomposite materials based on a high-performance epoxy system and single-walled carbon nanotubes (SWNTs) have been prepared. The noncovalent wrapping of nitric acid-treated SWNTs with a PEO-based amphiphilic block copolymer leads to a highly disaggregated filler with a boosted miscibility in the epoxy matrix, allowing its dispersion without organic solvents. Although direct dispersion of acid-treated SWNTs results in modestly improved epoxy matrix mechanical properties, the incorporation of wrapped SWNTs produces a huge increase in toughness (276% improvement at 0.5 wt % loading) and impact strength (193% at 0.5 wt % loading) with no detrimental effect on the elastic properties. A synergistic effect between SWNTs and the block copolymer is revealed on the basis of tensile and impact strength results. Atomic force microscopy has been applied, obtaining stiffness mappings that identify nanostructure features responsible of the dynamic mechanical behavior. The electrical percolation threshold is greatly reduced, from 0.31 to 0.03 wt % SWNTs when block copolymer-wrapped SWNTs are used, and all the measured conductivity values increased up to a maximum of 7 orders of magnitude with respect to the baseline matrix (1 wt % wrapped-SWNTs loading). This approach provides an efficient way to disperse barely dispersible SWNTs without solvents into an epoxy matrix, and to generate substantial improvements with small amounts of SWNTs.

4.
J Orthop Res ; 25(4): 495-500, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17205560

RESUMO

The purpose of this study was to determine what characteristics of fixation devices used in the treatment of osteochondritis dissecans (OCD) contribute to improved stability to resist shear loading. An OCD model was designed using rigid polyurethane foam. Each specimen consisted of two components, an osteochondral fragment and a corresponding defect. A total of 40 specimens were prepared and assigned to one of four groups: control (no extrinsic stabilizer); two 2-mm-diameter Kirschner wires (K-wires), 40 mm in length; one threaded washer and a 28-mm screw; and one threaded washer and a 38 mm screw. Each specimen was mounted onto an Iosipescu shear test fixture and subjected to shear loads at a pseudo-static displacement rate of 0.075 mm/s. All groups demonstrated some stability; controls were significantly less stable than all other groups. The group with the threaded washer and 38-mm screw demonstrated the greatest stability (p < 0.001), and no difference was noted between the K-wire and 28-mm screw groups. These results suggest that, in this OCD model, friction conferred some intrinsic stability to resist loads in shear. However, stability was improved with the use of long implants that compressed the fragments together.


Assuntos
Fixadores Internos , Instabilidade Articular/cirurgia , Teste de Materiais/métodos , Modelos Biológicos , Osteocondrite Dissecante/cirurgia , Artroplastia de Substituição/instrumentação , Artroplastia de Substituição/métodos , Fenômenos Biomecânicos , Parafusos Ósseos , Poliuretanos , Estresse Mecânico
5.
J Orthop Sci ; 11(2): 118-26, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16568382

RESUMO

Metal plates for internal fixation of fractures have been used for more than 100 years. Although initial shortcomings such as corrosion and insufficient strength have been overcome, more recent designs have not solved all problems. Further research is needed to develop a plate that accelerates fracture healing while not interfering with bone physiology. The introduction of rigid plates had by far the greatest impact on plate fixation of fractures. However, it led to cortical porosis, delayed bridging, and refractures after plate removal. These unwarranted effects were said to be caused by bone-plate contact interfering with cortical perfusion. Consequently, further plate modifications aimed to reduce this contact area to minimize necrosis and subsequent porosis. The advocates of limited-contact plates have not published measurements of the contact area or proof of the temporary nature of the porosis. Moreover, clinical studies of newer plate types have failed to show a superior outcome. Histomor-phometric measurements of the cortex showed no difference in the extent of necrosis under plates having different contact areas. Necrosis was predominant in the periosteal cortical half, whereas porosis occurred mostly in the endosteal cortical half. No positive correlation was found between either. The scientific evidence to date strongly suggests that bone loss is caused by stress shielding and not interference with cortical perfusion secondary to bone-plate contact. Consequently, an axially compressible plate (ACP) incorporating polylactide (PLA) inserts press-fit around screw holes was designed. The bioresorbable inserts should allow for (1) increased micromotion in the axial plane to promote healing during the union phase and (2) gradual degradation over time to decrease stress shielding during the remodeling phase. Results of ongoing experimental results are encouraging. Only plates allowing dynamic compression in the axial plane can lead to a revolution in fracture fixation.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas/instrumentação , Fixadores Internos , Animais , Materiais Biocompatíveis , Ensaios Clínicos como Assunto , Modelos Animais de Doenças , Fixação Interna de Fraturas/métodos , Consolidação da Fratura/fisiologia , Humanos , Teste de Materiais , Desenho de Prótese , Falha de Prótese , Fatores de Risco , Sensibilidade e Especificidade , Estresse Mecânico
6.
IEEE Trans Biomed Eng ; 52(10): 1792-5, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16235666

RESUMO

Mechanical testing of soft musculoskeletal structures like tendons and ligaments are essential to medical advances. A long-standing limitation for testing these structures in isolation has been the ability to solidly fix both ends of the tendon. Cryogenic fixation technology was leveraged into the development of a dual cryogenic fixation (DCF) device. Results of the study show that the DCF allows tendons to be tested in isolation, at physiologic temperatures, with excellent reproducibility.


Assuntos
Fenômenos Biomecânicos/instrumentação , Criopreservação/instrumentação , Ligamentos/fisiologia , Músculos/fisiologia , Estimulação Física/instrumentação , Tendões/fisiologia , Fixação de Tecidos/instrumentação , Animais , Fenômenos Biomecânicos/métodos , Criopreservação/métodos , Elasticidade , Desenho de Equipamento , Análise de Falha de Equipamento , Estimulação Física/métodos , Coelhos , Estresse Mecânico , Fixação de Tecidos/métodos
7.
J Hand Surg Am ; 29(1): 80-4, 2004 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-14751109

RESUMO

PURPOSE: To investigate the effect of the wafer procedure on pressure within the distal radioulnar joint. METHODS: The effect of increasing transverse distal ulnar head resection with preservation of the ulnar styloid was evaluated in 4 fresh frozen cadaver arms. Specimens were tested in neutral rotation. A standard transaxial load was applied from the radius to the ulna and the distal radioulnar joint intra-articular pressure was evaluated. RESULTS: Increasing amounts of distal ulnar resection led to a linear increase in pressure in the distal radioulnar articulation. CONCLUSION: The wafer procedure leads to an increase in pressure in the distal radioulnar joint that may lead to the early onset of osteoarthritis.


Assuntos
Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/métodos , Pressão , Articulação do Punho/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Cadáver , Feminino , Humanos , Masculino , Rádio (Anatomia)/fisiopatologia , Rádio (Anatomia)/cirurgia , Rotação , Ulna/fisiopatologia , Ulna/cirurgia , Articulação do Punho/cirurgia
8.
Arch Phys Med Rehabil ; 84(5): 662-7, 2003 May.
Artigo em Inglês | MEDLINE | ID: mdl-12736878

RESUMO

OBJECTIVE: To measure the biomechanical effects of immobilization on the Achilles' tendon. DESIGN: Experimental, controlled study. SETTING: Physiatry research laboratory. ANIMALS: Twenty adult rabbits. INTERVENTION: One hindlimb immobilized in a cast for 4 weeks (n=10) or 8 weeks (n=10). The contralateral legs (n=20) served as controls. MAIN OUTCOME MEASURES: Cross-sectional Achilles' tendon area, mode of failure, mean failure load, and tendon stiffness. RESULTS: The Achilles' tendon cross-sectional area did not change. Achilles' tendon-calcaneus units failed at insertion at 4 weeks and in controls. Calcaneus fracture was the most prevalent mode of failure at 8 weeks. The mean load to failure of both immobilized groups (4wk: 187.5+/-45.7N; 8wk: 162.6+/-39.3N) was significantly smaller than that of the control group (549.2+/-93.7N, both P<.005). The mean tendon stiffness of both immobilized groups (4wk: 64.6+/-24.8N/mm; 8wk: 53.9+/-19.9N/mm) was significantly lower than that of the control group (125.1+/-26.5N/mm, both P<.005). CONCLUSIONS: Immobility for up to 8 weeks caused decreased stiffness but no atrophy or rupture of the Achilles' tendon, suggesting that immobility does not constitute a risk factor for Achilles' tendon midsubstance rupture. Clinically, graded reloading is required after immobilization to restore the tendon insertion and to reverse calcaneal disuse osteoporosis.


Assuntos
Tendão do Calcâneo/lesões , Modelos Animais de Doenças , Elevação dos Membros Posteriores/efeitos adversos , Animais , Fenômenos Biomecânicos , Calcâneo/lesões , Moldes Cirúrgicos/efeitos adversos , Feminino , Fraturas Ósseas/etiologia , Fraturas Ósseas/patologia , Fraturas Ósseas/prevenção & controle , Osteoporose/etiologia , Osteoporose/patologia , Osteoporose/prevenção & controle , Coelhos , Amplitude de Movimento Articular , Fatores de Risco , Ruptura , Traumatismos dos Tendões/etiologia , Traumatismos dos Tendões/patologia , Traumatismos dos Tendões/prevenção & controle , Resistência à Tração , Fatores de Tempo , Suporte de Carga
9.
J Hand Surg Am ; 28(2): 332-41, 2003 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-12671868

RESUMO

PURPOSE: This study was conducted to determine the appropriateness of using the articular cartilaginous surfaces of the proximal tibiofibular joint to resurface damaged distal radial articular surfaces and to assess the clinical results in the first 2 patients. METHOD: Cadaveric specimens of the facets of the proximal tibiofibular joints and distal radius were sized and compared. Two patients underwent transfer of a fibular facet. RESULTS: The surface area of each of the proximal tibiofibular facets were larger than either the scaphoid or lunate facets of the distal radius. The 2 patients had excellent clinical results with minimal donor morbidity. CONCLUSIONS: Use of the articular surfaces from the proximal tibiofibular joint to replace damaged distal radial facets is possible and can be accomplished with excellent results and minimal morbidity.


Assuntos
Cartilagem Articular/transplante , Fraturas do Rádio/cirurgia , Adulto , Análise de Variância , Cadáver , Feminino , Fíbula , Humanos , Masculino , Pessoa de Meia-Idade , Fraturas do Rádio/diagnóstico por imagem , Tíbia , Tomografia Computadorizada por Raios X , Transplante Autólogo
10.
J Shoulder Elbow Surg ; 11(5): 504-9, 2002.
Artigo em Inglês | MEDLINE | ID: mdl-12378172

RESUMO

The goals of this study were to determine the strength of the supraspinatus tendon after reimplantation into a bony trough and to find out whether the fibrocartilaginous enthesis reformed. In 21 rabbits, the supraspinatus tendon was transected and reinserted into a bony trough at the greater tuberosity. After sacrifice at 8 and 12 weeks, tensile strength was measured. Microscopically, the presence of fibrocartilage and the spatial orientation of the cartilage columns and collagen fibers were assessed. At sacrifice, 14 of 21 reinserted specimens had healed successfully and were studied. Most mechanical failures occurred through bone, and none failed at the site of reimplantation. The mean peak loads of the operated tendons were significantly lower than their controls (8 weeks, 134.8 +/- 49.9 N vs 223.1 +/- 33.4 N, and 12 weeks, 172.2 +/- 68.2 N vs 274.1 +/- 70.0; P =.013 and P =.025, respectively). Histologically, at 8 weeks, the fibrocartilaginous enthesis had partially reformed; it was narrower than normal, and the collagen fibers had only partially assumed their normal spatial arrangement. Twelve weeks after reimplantation, 4 of 7 entheses had a normal histologic appearance. We conclude that return of strength of the supraspinatus tendon is evident 8 weeks after surgical reattachment into a bony trough and that the fibrocartilaginous enthesis is normal in over half of the specimens at 12 weeks. The subchondral bone was weaker than the reinserted tendon. The results support the clinical practice of surgical reimplantation. Avoiding active exercises early while promoting them later could improve the surgical results and reduce the effects of disuse.


Assuntos
Reimplante , Tendões/parasitologia , Tendões/transplante , Animais , Período Pós-Operatório , Coelhos , Tendões/citologia , Resistência à Tração
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