[Energy metabolism in students depending on motivation during exams]. / Energoobmen u studentov vo vremia ékzamena v zavisimosti ot urovnia motivatsii.

The energy metabolism (EM) was shown to significantly depend upon the motivation level in students during examination. Energy expenditure increased before the examination in low- and medium motivation groups but not in highly motivated students.

[P.K. Anokhin's theory of functional systems in the study of psychophysiological parameters of students' efficacious activity]. / Teoriia funktsional'nykh sistem P.K. Anokhina v izuchenii psikhofiziologicheskikh pokazatelei rezul'tativnoi deiatel'nosti studentov.

Psychophysiological characteristics of students' efficacious educational activity were studied in the context of P. K. Anokhin's theory of functional systems. Autonomic functions and dysfunctions and energy expenditures were measured in students during their daily educational activity and after oral examinations. Their physiological characteristics and personality traits were shown to be related to the results achieved by the students--to their marks got at examinations and to their reaction of satisfaction/dissatisfaction with their marks. The students who were satisfied with marks showed increased anxiety, vegetative vascular dystonia, and profound changes in energy expenditures and autonomic functions, i.e. a high physiological price for educational success. The students who failed displayed low physiological expenditures manifested by extraversion and were apparently healthy.

[Preclinical ECG changes and their evaluation based on the criterion of symmetrical approach]. / Doklinicheskie izmeneniia EKG i ikh kriterial'naia otsenka na osnove simmetriinogo podkhoda.

To reveal preclinical cardiac performance changes, conventional and unique ECG processing procedures were used in 101 individuals. A classification of heart function was developed, which was based on a comprehensive assessment of ECG. The results of the clinicofunctional classification were well comparable with those of a quantitative ECG analysis made with heuristical methods. The ratios of various ECG parameters are more informative than the absolute values of these parameters. In screening, the quantitative ECG analysis have some advantages over the visual one as it requires no thorough clinicopharmacological study. The symmetrical approach to an ECG analysis with the use of geometrical methods of simulation may be useful for the criterion assessment of preclinical alteration in cardiac performance.

[Distribution of labeled amino acids and delta-sleep inducing peptide in the body after instillation into the conjunctiva of the rabbit eye]. / Raspredelenie mechenykh aminokislot i peptida, vyzyvaiushchego del'ta-son, v organizme pri instiliatsii na kon"iunktivu glaza krolika.

Dynamics of 3H-valine, 3H-glycine and 3H-DSIP distribution in various brain structures, tissues and liquids of an organism due to administration of these substances in eye conjunctive were studied in rabbits with scintillation spectrometry method. Marked amino acids and DSIP were observed in all substrates in 10 min after administration. Maximal activity was found in 2 h in the brain visual cortex and in 30 min in cardiac tissue, spleen and optical chiasma.

[Parasympathetic regulation of cardiac rhythm in delta sleep-inducing peptide deficiency]. / Parasimpaticheskaia reguliatsiia serdechnogo ritma v usloviiakh defitsita peptida del'ta-sna v organizme.

The effect of delta-sleep peptide (DSP) deficiency on the parasympathetic regulation of the heart rate was studied on 35 rabbits. It was established that the injection of an-serum (titer-1:2000-1:3000) leads to the attenuation of parasympathetic influences: heart rate increase in freely behaving animals and a decrease in negative chronotropic effect with direct vagus irritation. Antiserum, like DSP, administration causes practically no damage of the myocardial ultrastructure.

[Endogenous peptides in the organization of somato-vegetative responses to hypothalamic stimulation]. / Endogennye peptidy v organizatsii somatovegetativnykh reaktsii pri stimuliatsii gipotalamusa.

The effect of i. v. administration of angiotensin II, substance P, DSIP, B-endorphin and bradykinin on the behaviour and the somato-vegetative responses to electrical stimulation of negative and positive emotiogenic regions of the hypothalamus, were studied. Angiotensin II, substance P and DSIP suppressed the avoidance and self-stimulation responses and inhibited cardiovascular responses. Bradykinin, renin and B-endorphin increased the latency of avoidance responses, enhanced and prolonged the somato-vegetative responses to electrical stimulation of negative emotiogenic regions of the hypothalamus. Possible mechanisms of the peptides physiological activity are discussed.

[Role of the lateral hypothalamus in the genesis of somato-autonomic responses]. / Rol' lateral'nogo gipotalamusa v geneze somato-vegetativnykh reaktsii.

Coagulation of medial and lateral parts of the lateral hypothalamic area increases latency of responses and decreases respiration, arterial blood pressure and heart rate responses to stimulation of the hypothalamic ventromedial nucleus. Coagulation of the perifornical region of the lateral hypothalamus completely eliminates the above autonomic responses. A new rigid integration which is characterized with the increased number of correlated relations between separate components of somato-autonomic responses, was postulated after correlation analysis of somato-autonomic parameters during stimulation of hypothalamic ventromedial nucleus in animals with lateral hypothalamic lesions. The data suggest that somato-autonomic responses to stimulation of negative emotion sites of the hypothalamus are mediated by those brain structures which are under ascending excitatory influences of the lateral hypothalamus.

[Comparative characteristics of the self-stimulation response in rabbits following administration of angiotensin II into the cerebral ventricles and application to the conjunctiva]. / Sravnitel'naia kharakteristika reaktsii samorazdrazheniia u krolikov pri vvedenii angiotenzina II v zheludochki mozga i pri applikatsii na kon"iunktivu glaza.

Experiments on rabbits have shown that intraventricular administration of angiotensin II induces the dose-dependent suppression of the self-stimulation reaction after varying intervals. The same suppression of the self-stimulation in rabbits but after a greater interval is produced by the application of angiotensin aqueous solution to the eye conjunctiva. In both cases the amount of drinking reactions in the animals significantly rises after the oligopeptide administration as compared with controls. Examination of the time course of arterial pressure, respiration and ECG has shown that only intravenous injection of angiotensin II in doses of 500 ng provokes a temporary increase in arterial pressure, marked bradycardia and changes in respiration, whereas other routes of administration produce no changes in the characteristics studied.

[Experimental reproduction of a secondary pacemaker center for alimentary motivation]. / Eksperimental'noe vosproizvedenie dubliruiushchego peismekernogo tsentra pishchevoi motivatsii.

In chronic experiments on rabbits the possibility of artificial modeling of motivational feeding pacemaker's function by different limbic-reticular structures was investigated. It was shown that simultaneous stimulation of the lateral hypothalamic "feeding" centre with various structures of the limbic-reticular complex makes secondary pacemaker of feeding motivation in the midbrain reticular formation only.