Deep Anomaly Detection Framework Utilizing Federated Learning for Electricity Theft Zero-Day Cyberattacks.

Smart power grids suffer from electricity theft cyber-attacks, where malicious consumers compromise their smart meters (SMs) to downscale the reported electricity consumption readings. This problem costs electric utility companies worldwide considerable financial burdens and threatens power grid stability. Therefore, several machine learning (ML)-based solutions have been proposed to detect electricity theft; however, they have limitations. First, most existing works employ supervised learning that requires the availability of labeled datasets of benign and malicious electricity usage samples. Unfortunately, this approach is not practical due to the scarcity of real malicious electricity usage samples. Moreover, training a supervised detector on specific cyberattack scenarios results in a robust detector against those attacks, but it might fail to detect new attack scenarios. Second, although a few works investigated anomaly detectors for electricity theft, none of the existing works addressed consumers' privacy. To address these limitations, in this paper, we propose a comprehensive federated learning (FL)-based deep anomaly detection framework tailored for practical, reliable, and privacy-preserving energy theft detection. In our proposed framework, consumers train local deep autoencoder-based detectors on their private electricity usage data and only share their trained detectors' parameters with an EUC aggregation server to iteratively build a global anomaly detector. Our extensive experimental results not only demonstrate the superior performance of our anomaly detector compared to the supervised detectors but also the capability of our proposed FL-based anomaly detector to accurately detect zero-day attacks of electricity theft while preserving consumers' privacy.

Colchicine ameliorates the chronic inflammatory state in patients with chronic rheumatic valvular heart disease: a pilot study.

BACKGROUND: Inflammation is an important contributor to the pathogenesis of rheumatic heart disease (RHD). High serum levels of C-reactive protein (CRP) and interleukin-6 (IL-6) are commonly seen in patients with chronic (RHD) and indicate the presence of a chronic inflammatory state. The aim of this study was to assess the effect of colchicine as anti-inflammatory drug on the serum levels of the inflammatory markers (CRP) and (IL-6) in patients with chronic (RHD). RESULTS: This is a prospective controlled study that enrolled thirty-five patients with chronic (RHD) visiting Ain Shams University Hospital's outpatient clinic for receiving regular long acting penicillin as rheumatic fever prophylaxis. Ten matched healthy individuals were taken as control group. Blood samples for serum levels of CRP and IL-6 were collected before and 1 month after receiving colchicine 0.5 mg BID. Mean (CRP) level was 6.09 ± 4.39 IU/ml versus 0 IU/ml in the control group respectively (P = 0.0001). Mean (IL-6) level was 113.57 ± 37.41 ng/l versus 10.50 ± 5.99 ng/l, in the control group (p = 0.0001). Mean (CRP) was 6.09 ± 4.39 IU/ml before and became 3.34 ± 3.07I U/ml 1 month after colchicine therapy. Mean (IL-6) level was 113.57 ± 37.4 ng/l before and became 45.57 ± 20.39 ng/l 1 month after colchicine therapy (P = 0.001). CONCLUSION: In this pilot study, using colchicine as anti-inflammatory drug in patients with chronic (RHD) significantly reduced the serum inflammatory markers (CRP) and (IL-6), thus helping in ameliorating their chronic inflammatory state.

Successful Endoscopic Management of a Renal Fungal Ball using Flexible Ureterorenoscopy.

BACKGROUND: Candida as a cause for urinary tract infection in healthy individuals is unusual. The extension of fungi into the urinary collecting system rarely leads to formation of bezoars or fungus balls. This can in turn lead to hydronephrosis, obstructive uropathy and sepsis. CASE PRESENTATION: An eighty years old gentleman presented to A&E with confusion, severe urosepsis and acute kidney injury. CTKUB demonstrated significant right sided hydronephrosis, perinephric fat stranding and gas in collecting system. A year prior to this admission he has become known to the urology team for a fungal ball that was noted in the upper pole of the right kidney which was picked up following elective flexible ureterorenoscopy for right kidney stones. Flexible ureterorenoscopy and successful retrieval of fungal ball by basket was performed. CONCLUSION: We advocate this technique to be considered as an alternative to the current treatment offered to patients with fungal ball infections and especially so in cases were a nephrostomy is either contraindicated, unavailable, or not possible.

Molecular rearrangement. 36. Selective alpha-CH oxidation of alkylarenes by nitrogen dioxide on thermolysis with nitramines.

Thermolysis of 2,4,6-trichloro-N-nitroaniline 1 and N-methyl-2,4-dinitro-N-nitroaniline 2 each with primaryl alkylbenzenes led to the formation of acylbenzenes. Similar reactions with secondary alkylbenzenes afforded a mixture of acetophenone and aliphatic aldehydes. Use of tert-butylbenzene in this reaction yielded formaldehyde and 2,3-diphenyl-2,3-dimethylbutane. The mechanisms of the studied reactions are discussed.