RESUMO
The function of beta-adrenergic receptors was assessed in 50 children with asthmatic bronchitis and 45 healthy controls by the hyperglycemic, eosinopenic and platelet aggregation responses to epinephrine. The results showed evidence of beta-adrenergic blockade in children with asthmatic bronchitis. It is suggested that this blockade may reflect a functional and/or a structural immaturity of the beta receptors in these children.
Assuntos
Asma/fisiopatologia , Receptores Adrenérgicos beta/efeitos dos fármacos , Receptores Adrenérgicos/efeitos dos fármacos , Glicemia , Pré-Escolar , Eosinófilos , Epinefrina/farmacologia , Feminino , Humanos , Hiperglicemia/etiologia , Lactente , Contagem de Leucócitos , Masculino , Agregação Plaquetária/efeitos dos fármacosAssuntos
Albuterol/uso terapêutico , Coqueluche/tratamento farmacológico , Albuterol/administração & dosagem , Criança , Pré-Escolar , Cloranfenicol/administração & dosagem , Cloranfenicol/uso terapêutico , Quimioterapia Combinada , Humanos , Lactente , Prednisona/administração & dosagem , Prednisona/uso terapêuticoRESUMO
The tonsils were studied histologically and histochemically in 67 children with rheumatic heart disease, 33 children with chronic tonsillitis and 5 normal children. The tonsils of rheumatic children showed hyperplasia and hyperactivity of lymphocytes and paucity of phagocytes. It was suggested that these peculiar findings might contribute to the pathogenesis of rheumatic fever.
