[Alternative of laser treatment optimization in retinoschisis].

In this study a new original technique is proposed for treatment of II-III retinoschisis using diode laser Milon Lachta (Saint-Petersburg). Laser radiation parameters were wave length 0,83 microm, energy 350-850 m W, time 0,2-0,3 s, spot diameter 150-200 microm. Original technique of gradual progressive laser coagulation was performed in 72 patients with II-I1 retinoschisis using diode laser. This treatment allowed to preserve macular function to the maximum.

[An experimental action of new injection-scleroplasty substance on eye tissues]. / Eksperimental'noe issledovanie vliianiia novogo materiala dlia "in''ektsionnoi" skleroplastiki na tkani glaza.

An experimental study was made with 8 eyes of chinchilla rabbits for the purpose of investigating the interplay between the allotransplant (administered in the Tenon's space of the eyes of experimental animals), suggested by us, on the one hand, and the neighboring ocular components, on the other hand. According to the results, the used substance is subject to necrolysis accompanied by an induced local inflammation response. As the substance dissolved, it was found to be displaced by connective tissue. At first, the tissue was granulated, then, it became more compact with its structure resembling the sclera; the tissue tightly abutted the latter intensifying its properties. It is noteworthy, that the inflammation zone was limited to the administration region. With due respect to the above, it can be stated that the suggested method can be clinically used in future as a full sclera-fixing procedure.

[Influence of adaptation of hypoxia on the relationship between tissue respiration, temperature and oxygen tension in vitro]. / Vliianie adaptatsii k gipoksii nazavisimost' tkanevogo dykhaniia ot temperatury i napriazheniia kisloroda in vitro.

The effect of adaptation to hypoxia on rat tissue respiration at different pO2 and temperature in vitro was studied. The temperature coefficient Q10 and the Michaelis constant Km for oxygen were estimated. The tissue sensitivity to low pO2 and low temperature obviously decreased while the tissue affinity for oxygen and the direct temperature dependence on Km increased in animals adapted to hypoxia. A functional interrelationship between adaptational changes of Q10 and Km of tissue respiration in different organs was revealed. The data obtained suggest participation of cellular oxidation changes in adaptive increase of oxygen affinity.