RESUMO
Although AIDS has had a huge impact around the world, nowhere has its effect been greater than in Africa. In Zambia alone the disease is expected to create 500,000 orphans by the turn of the century. In this article Dr. Rachel Baggaley and Dale Needham examine the huge social problems AIDS is creating in some of the world's poorest countries.
Assuntos
Síndrome da Imunodeficiência Adquirida/epidemiologia , Surtos de Doenças/estatística & dados numéricos , Cuidados no Lar de Adoção/estatística & dados numéricos , Complicações Infecciosas na Gravidez/epidemiologia , Problemas Sociais , Síndrome da Imunodeficiência Adquirida/prevenção & controle , África/epidemiologia , Criança , Surtos de Doenças/prevenção & controle , Feminino , Humanos , Masculino , Educação de Pacientes como Assunto , GravidezRESUMO
At Makthlawaiya, in the Paraguayan Chaco, the prevalence of Trypanosoma (Schizotrypanum) cruzi infection among both domestic Triatoma infestans and domestic dogs was 38%, and IgG anti-T. cruzi antibody was detected by the quantitative enzyme-linked immunosorbent assay (ELISA) in 80% (105/133) of human sera. Ninety percent (25/28) of T. cruzi strains isolated from both T. infestans and dogs showed heterozygous isoenzyme profiles for glucose phosphate isomerase, phosphoglucomutase and 6-phosphogluconate dehydrogenase. These strains appeared to be closely related to Bolivian zymodeme 2. Three Paraguayan T. cruzi strains showed homozygous isoenzyme profiles, similar to those of major Brazilian zymodemes. It was concluded that T. cruzi strains with heterozygous isoenzyme profiles predominate in domestic transmission cycles in this highly endemic area of the Paraguayan Chaco.
