RESUMO
Serum zinc levels in acne patients and in matched healthy controls of both sexes and within the same age group (16-20 years age) were estimated. Women, whether diseased or healthy, have shown a significantly lower mean serum zinc level than the corresponding men. In advanced grades of acne, both men and women have a significantly lower level than the corresponding control groups. Within the same sex group, those with advanced grades have revealed a significantly lower level than those with slight grades.
Assuntos
Acne Vulgar/sangue , Zinco/sangue , Acne Vulgar/etiologia , Adolescente , Adulto , Feminino , Humanos , Masculino , Fatores Sexuais , Vitamina A/fisiologia , Zinco/deficiência , Zinco/fisiologiaAssuntos
Cobre/metabolismo , Transtornos da Pigmentação/metabolismo , Adulto , Feminino , Humanos , MasculinoAssuntos
Anticoncepcionais/farmacologia , Norgestrienona/farmacologia , Norpregnatrienos/farmacologia , Animais , Implantes de Medicamento , Estrogênios/sangue , Feminino , Macaca mulatta , Menstruação , Norgestrienona/administração & dosagem , Norgestrienona/análogos & derivados , Norgestrienona/sangue , Progesterona/sangueRESUMO
The effect of Quinestrol (3-0-cyclopentyl-17alpha-ethinyl-1, 3, 5 (10)-triene-3,17-diol), a long acting estrogenic contraceptive steroid, on plasma lipids has been studied in ten women for three months. It was found to lower plasma free fatty acids, cholesterol and cholesterol esters, but to increase plasma phospholipids and triglycerides. The possible causes of these alterations are discussed.
Assuntos
Lipídeos/sangue , Norpregnatrienos/farmacologia , Quinestrol/farmacologia , Adolescente , Adulto , Colesterol/sangue , Ésteres do Colesterol/sangue , Depressão Química , Ácidos Graxos não Esterificados/sangue , Feminino , Humanos , Fosfolipídeos/sangue , Estimulação Química , Triglicerídeos/sangueAssuntos
Lactação/efeitos dos fármacos , Norgestrienona/análogos & derivados , Norpregnatrienos/análogos & derivados , Período Pós-Parto , Congêneres da Progesterona/farmacologia , Animais , Animais Recém-Nascidos , Peso Corporal , Implantes de Medicamento , Feminino , Haplorrinos , Macaca mulatta , Leite/metabolismo , Norgestrienona/metabolismo , Norgestrienona/farmacologia , Gravidez , Congêneres da Progesterona/sangue , Congêneres da Progesterona/metabolismoRESUMO
The effects of Depoprovera and Deladroxone were studied in humans, on certain milk components as well as on the growth of the nursed infants. Both drugs caused reduction in milk yield. Both drugs caused an increase in the concentration of milk total proteins, however. Depoprovera caused an increase while Deladroxone caused a decrease in the total amount of milk proteins per feed. Depoprovera showed no effect while Deladroxone caused an increase in the concentration of milk lipids; however, both drugs caused reduction in the total amount of milk lipids per feed. Both drugs showed no effect on the concentration of milk lactose, but caused reduction in the total amount of milk lactose per feed. The percentage increase in weight of nursed infants was decreased by Depoprovera, but not affected by Deladroxone.
PIP: The effects of Depo Provera and Deladroxone, both long-acting inject able contraceptive agents, on lactation and infant growth was studied in 76 lactating women. Milk yield was decreased by both drugs, though the concentration of total milk proteins was increased. Depo Provera increased the total amount of milk proteins per feed, while a decrease was observed with Deladroxone. Deladroxone increased the concentration of milk lipids, but Depo Provera had no effect. Nonetheless, both agents reduced the total amount of milk lipids per feed. Concentrations of milk lactose were unaffected, but the total amount of milk lactose per feed was reduced by both drugs. Depo Provera decreased the rate of infant growth, while Deladroxine had no effect.
