RESUMO
Dust particles (DPs) are one of the most important public health concerns in the urban environment. The presence of heavy metals (HMs) on the surface of DPs might increase the health risk of exposure to the DPs. Accordingly, The purpose of this study was to examine the content of HMs in the outdoor and indoor DPs in Neyshabur city and assess the cytotoxic effects of DPs exposure on lung, gastric, and skin cell lines. To this end, the city was divided into three areas, high-traffic, medium-traffic, and low-traffic (rural). The average concentration of the HMs in the indoor DPs were as follows, 655.5 µg g-1 for Zn, 114.6 µg g-1 for Cu, 77.7 µg g-1 for Cr, 108.6 µg g-1 for Ni, 52 µg g-1 for Pb, 12 µg g-1 for Co, and 3.3 µg g-1 for Cd, while the average concentration of Zn, Cu, Cr, Ni, Pb, Co, Cd in the outdoor DPs were 293.7 µg g-1, 200.6 µg g-1, 100.7 µg g-1, 68.4 µg g-1, 44.7 µg g-1, 18.6 µg g-1, 0.25 µg g-1, respectively. A higher concentration of HMs, as well as cytotoxicity, were revealed in the indoor samples compared to outdoor ones. The degree of cytotoxicity of DPs collected from high-traffic areas was higher than that of low and medium-traffic ones. In addition, treatment of AGS and L929 cells with indoor dust samples induced the expression level of inflammatory agents such as TNFα, IL6, and, CYP1A1 genes more than in outdoor dust samples (P < 0.05). Briefly, a higher level of HMs concentration and cytotoxicity effect on the given cell lines was observed in the samples taken from indoor environments and high-traffic areas.
RESUMO
The purpose of this study was to determine the effect of mindfulness-based art therapy (MBAT) in decreasing stress and improving on pregnant women's life style in Neyshabur, Iran 2018. The participants of the present quasi-experimental study were 84 pregnant women. The findings showed that the MBAT group demonstrated a significant decrease in symptoms of distress and significant improvements in key aspects of the health-related style of life as measured by Health Promoting Lifestyle Profile-II questionnaire. Moreover, it was found that the MBAT intervention had a significant effect on improving lifestyle behaviours (p < .05). The highest mean score of lifestyle was for the sub-domain of nutrition (31.35 ± 5.34), while the lowest score was achieved by the sub-domains of physical activity (13.55 ± 1.89).The mean (SD) score of stress management was (19.12 ± 1.54). This investigation of MBAT provides initial encouraging data that support a possible future role for the intervention as a psychosocial option for decreasing symptoms of distress in pregnant women and improving their lifestyle.Impact statementWhat is already known on this subject? Mindfulness-based art therapy is a blend of basic meditation principles and art therapy. The results of this study showed that mindfulness-based art therapy (MBAT) could decrease the stress and improve lifestyle behaviours in pregnant women.What do the results of this study add? The results of the present study showed that mindfulness-based art therapy (MBAT) during pregnancy decreased the stress and improved life style. It is believed that changing lifestyle to include mind-body medicine such as MBAT in pregnant women will greatly reduce stress responses, and help protect pregnant women from disease during pregnancy.What are the implications of these findings for clinical practice and/or further research? The study showed the important role of mindfulness-based art therapy (MBAT) during pregnancy in reducing stress and improving life style.
