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Turk J Gastroenterol ; 26(6): 498-505, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26510081

RESUMO

BACKGROUND/AIMS: To evaluate the short-term outcome of the decision taken by the Hepatoma Board for the treatment of Hepatocellular carcinoma (HCC). MATERIALS AND METHODS: This was a prospective descriptive study involving 74 patients with HCC diagnosed by the known criteria. The decisions taken by the Hepatoma Board for the 74 patients were as follows: 1- surgical resection (7 patients), 2- local ablative therapy (LAT) (22 patients), 3- conventional transarterial chemoembolization (TACE) (24 patients), and 4- palliative supportive care (21 patients). RESULTS: The short-term mortality rate was 25.7% of the total patients. The success rate was nearly equal in LAT (68.2%) and surgery (71.4%), whereas the success rate was approximately 33.3% in TACE. There was no difference in the mean total bilirubin level before and after LAT, surgery, or TACE (p>0.05 for each). There was a significant decrease in the mean serum albumin level after TACE (p=0.000). There was a decrease in the mean alpha fetoprotein level after surgery and LAT (p=0.033) for surgery and (p=0.048) for LAT. CONCLUSION: The management of HCC is better performed through a multidisciplinary team decision. Surgery has comparable outcome to LAT but is more invasive. According to our local experience, conventional TACE has a success rate of 33.3%.


Assuntos
Carcinoma Hepatocelular/terapia , Tomada de Decisão Clínica/métodos , Gerenciamento Clínico , Neoplasias Hepáticas/terapia , Equipe de Assistência ao Paciente , Técnicas de Ablação/mortalidade , Adulto , Idoso , Bilirrubina/sangue , Carcinoma Hepatocelular/sangue , Carcinoma Hepatocelular/mortalidade , Quimioembolização Terapêutica/mortalidade , Feminino , Humanos , Fígado/cirurgia , Neoplasias Hepáticas/sangue , Neoplasias Hepáticas/mortalidade , Masculino , Pessoa de Meia-Idade , Cuidados Paliativos , Estudos Prospectivos , Albumina Sérica/análise , Resultado do Tratamento , alfa-Fetoproteínas/análise
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