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1.
Med Biol Eng Comput ; 61(7): 1649-1660, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36848010

RESUMO

The study aimed to develop a clinical diagnosis system to identify patients in the GD risk group and reduce unnecessary oral glucose tolerance test (OGTT) applications for pregnant women who are not in the GD risk group using deep learning algorithms. With this aim, a prospective study was designed and the data was taken from 489 patients between the years 2019 and 2021, and informed consent was obtained. The clinical decision support system for the diagnosis of GD was developed using the generated dataset with deep learning algorithms and Bayesian optimization. As a result, a novel successful decision support model was developed using RNN-LSTM with Bayesian optimization that gave 95% sensitivity and 99% specificity on the dataset for the diagnosis of patients in the GD risk group by obtaining 98% AUC (95% CI (0.95-1.00) and p < 0.001). Thus, with the clinical diagnosis system developed to assist physicians, it is planned to save both cost and time, and reduce possible adverse effects by preventing unnecessary OGTT for patients who are not in the GD risk group.


Assuntos
Aprendizado Profundo , Diabetes Gestacional , Humanos , Feminino , Gravidez , Diabetes Gestacional/diagnóstico , Estudos Prospectivos , Teorema de Bayes , Aprendizado de Máquina
2.
Int J Gynaecol Obstet ; 161(2): 525-535, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36306416

RESUMO

OBJECTIVE: To define risk factors for the early prediction of gestational diabetes mellitus (GDM) because the risk of pre-eclampsia and preterm birth increases in mothers who are diagnosed with GDM. MATERIALS AND METHODS: A prospective study was designed and the data were collected by physicians prospectively from the patients who came to the clinic between the years 2019 and 2021; informed consent was obtained from the women. The prospective data comprised 489 patient records with 72 variables and the risk factors for early prediction of GDM were determined using logistic regression and random forest (RF), which is an advanced analysis method. RESULTS: The obtained sensitivity and specificity values are 90% and 75% for logistic regression and 71% and 90% for the RF, respectively. CONCLUSION: In this prospective study of GDM in Turkish women; age, body mass index, level of hemoglobin A1c, level of fasting blood sugar, physical activity time in first trimester, gravidity, triglycerides, and high-density lipoprotein cholesterol were confirmed to be risk factors in analysis results.


Assuntos
Diabetes Gestacional , Nascimento Prematuro , Gravidez , Humanos , Recém-Nascido , Feminino , Diabetes Gestacional/diagnóstico , Diabetes Gestacional/epidemiologia , Estudos Prospectivos , Fatores de Risco , Primeiro Trimestre da Gravidez , Índice de Massa Corporal , Glicemia/análise
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