RESUMO
The aim of this study was to determine the prevalence of hypertensive retinopathy, features of hypertensive retinopathy and visual outcome in hypertensive disorders in pregnancy in Hospital Universiti Sains Malaysia, Kelantan, Malaysia. A prospective observational hospital based study involving 154 patients (308 eyes) with hypertensive disorders in pregnancy was conducted. All subjects were examined once during antenatal period, at a minimum of 35 weeks of gestation for blood pressure, visual acuity and funduscopy. The similar protocol was repeated at six weeks postnatal period. Thirty-two point five percent had hypertensive retinopathy. Ninety eight percent had visual acuity 6/6 during antenatal assessment, while 100.00% gained 6/6 at postnatal period. Generalized arteriolar narrowing was the most common retinopathy observed. There was no statistically significant association between presence of hypertensive retinopathy and maternal age, presenting visual acuity, systolic/diastolic blood pressure (p>0.05). We conclude that prevalence of hypertensive retinopathy is 32.5%, and majority had good visual acuity during antenatal and postnatal period. Hypertensive retinopathy is insignificantly associated with maternal age, presenting visual acuity and blood pressure.
Assuntos
Hipertensão , Retinopatia Hipertensiva , Pressão Sanguínea , Retinopatia Diabética , Feminino , Humanos , Hipertensão/epidemiologia , Gravidez , Estudos Prospectivos , Doenças RetinianasRESUMO
Sinusitis is a rare cause of optic neuritis in children. This case illustrates bilateral optic neuritis in a 9-year-old child caused by pansinusitis. It demands an accurate diagnosis with a prompt management. A proper treatment of sinusitis is essential to prevent this complication.
Assuntos
Neurite Óptica/etiologia , Sinusite/complicações , Combinação Amoxicilina e Clavulanato de Potássio/uso terapêutico , Sedimentação Sanguínea , Criança , Quimioterapia Combinada , Lateralidade Funcional , Glucocorticoides/uso terapêutico , Humanos , Contagem de Leucócitos , Imageamento por Ressonância Magnética , Masculino , Neurite Óptica/diagnóstico , Neurite Óptica/tratamento farmacológico , Sinusite/diagnóstico , Sinusite/tratamento farmacológico , Tomografia Computadorizada por Raios X , Transtornos da Visão/diagnóstico , Transtornos da Visão/tratamento farmacológico , Transtornos da Visão/etiologia , Acuidade Visual/fisiologiaRESUMO
We reported a case of orbital rhabdomyosarcoma with an intracranial extension in an HIV-infected child. It was an uncommon sarcoma in a retroviral-positive patient that resulted in a diagnostic and therapeutic dilemma. The child is currently asymptomatic following surgery, chemotherapy, and reinstitution of highly active retroviral therapy (HAART).
Assuntos
Neoplasias Encefálicas/patologia , Infecções por HIV/transmissão , Transmissão Vertical de Doenças Infecciosas , Neoplasias Orbitárias/patologia , Neoplasias dos Seios Paranasais/patologia , Rabdomiossarcoma Embrionário/patologia , Terapia Antirretroviral de Alta Atividade , Neoplasias Encefálicas/diagnóstico por imagem , Neoplasias Encefálicas/cirurgia , Relação CD4-CD8 , Criança , Craniotomia , Infecções por HIV/diagnóstico , Infecções por HIV/tratamento farmacológico , Humanos , Masculino , Invasividade Neoplásica , Neoplasias Orbitárias/diagnóstico por imagem , Neoplasias Orbitárias/cirurgia , Neoplasias dos Seios Paranasais/diagnóstico por imagem , Neoplasias dos Seios Paranasais/cirurgia , Rabdomiossarcoma Embrionário/diagnóstico por imagem , Rabdomiossarcoma Embrionário/cirurgia , Tomografia Computadorizada por Raios XRESUMO
PURPOSE: To describe recurrent peripheral ulcerative keratitis (PUK) on the corneoscleral graft in a young man treated successfully with oral corticosteroids. METHODS: Interventional case report. RESULTS: A 21-year-old Malay man with no previous known medical illnesses presented with a sudden onset of peripheral corneal perforation. It was temporarily sealed with a multilayer amniotic membrane followed by patching with a corneoscleral button. One month later, a recurrence of PUK on the donor button was noted. It was successfully treated with oral corticosteroids. CONCLUSIONS: PUK without systemic manifestation may recur in the donor corneoscleral graft. Prompt intensive treatment with oral corticosteroids results in a favorable outcome.
Assuntos
Transplante de Córnea , Úlcera da Córnea/prevenção & controle , Glucocorticoides/uso terapêutico , Prednisolona/uso terapêutico , Esclera/transplante , Administração Oral , Adulto , Âmnio/transplante , Anti-Infecciosos/administração & dosagem , Ciprofloxacina/administração & dosagem , Úlcera da Córnea/cirurgia , Quimioterapia Combinada , Humanos , Masculino , Recidiva , Ruptura EspontâneaRESUMO
INTRODUCTION: Corneal ulceration remains one of the major causes of blindness in developing countries, including Malaysia. Our objective is to determine the epidemiological characteristics, clinical features, risk factors and the aetiology of microbial keratitis in patients admitted to Hospital Universiti Sains Malaysia (HUSM). METHODS: All patients with microbial keratitis admitted to our hospital over a 16-month period from January 2004 to April 2005 were included in the study. Sociodemographic data and information pertaining to risk factors were recorded. All patients underwent examination with slit lamp biomicroscopy and corneal scrapings were sent for microbiological diagnosis. RESULTS: 42 patients were included in the study; 26 were male and 16 were female, with mean age of 44.5 (+/- 20.9) years. History of previous corneal trauma was present in 26 (61.9 percent) patients. Central location ulcers were more predominant (69 percent) than peripheral ulcers. Cultures from corneal scrapings were positive in 29 cases (69 percent). Of those individuals with positive cultures, 23 (79.3 percent) had pure bacterial infection, four (13.8 percent) had pure fungal infection and two (6.9 percent) had mixed growth. The most common bacterial pathogen isolated was Pseudomonas aeruginosa (40.5 percent), followed by Streptococcus pneumoniae (7.5 percent). Fungal pathogens which were isolated include Fusarium spp. (4.7 percent) and Aspergillus spp. (2.4 percent). CONCLUSION: Central corneal ulceration is a problem among patients presenting with microbial keratitis in HUSM. It often occurs after corneal trauma. These findings have important public health implications for the treatment and prevention of visual morbidity due to an infective cause.