Basal cell adenoma of the deep lobe of the parotid gland misdiagnosed as mucoepidermoid carcinoma - A case report.

INTRODUCTION: Basal cell adenoma is a rare, benign epithelial tumour of the salivary gland, comprising only 1-2 % of all salivary gland tumours. Predominantly found in the parotid gland, basal cell adenoma can also occur in minor salivary glands and are often confused with other benign and malignant salivary gland tumours. A thorough histopathological examination can provide a definitive diagnosis. PRESENTATION OF CASE: A 65-year-old woman presented with a painless mass in the right infra-auricular region. Imaging revealed a well-defined hypodense lesion in the deep lobe of the right parotid gland, initially suspected as mucoepidermoid carcinoma. Fine needle aspiration was inconclusive, leading to the decision to perform a total conservative parotidectomy. Histopathology confirmed basal cell adenoma, characterized by cystic areas filled with mucoid material and basaloid cells arranged in trabecular and tubular patterns. DISCUSSION: Basal cell adenoma was classified as a distinct entity by the WHO in 1991. Cytologically, they imitate both benign and malignant salivary as well as non-salivary gland tumours. The histological hallmark of basal cell adenoma involves basaloid cells with small round nuclei showing no atypia, scant pale cytoplasm, and distinct peripheral palisading. Treatment involves surgical removal, with a more radical approach for certain variants such as the membranous type. CONCLUSION: This case highlights the clinical, radiological, and histopathological features of basal cell adenoma, emphasizing the importance of accurate diagnosis and appropriate surgical management. Early detection and appropriate treatment are crucial for optimizing patient outcomes in basal cell adenoma management.

Bridging Dehydrogenation and Hydrogenation in Heterogeneous Catalysis: A Demonstration of a Unified Catalytic Approach.

In the pursuit of enhancing the applications of hydrogen as an energy carrier, this research delved into the utilization of a singular hybrid catalyst capable of performing both dehydrogenation and hydrogenation processes for Liquid Organic Hydrogen Carriers (LOHCs). This study presents the synthesis and characterization of a hybrid catalyst, combining an organometallic pincer complex with Pd-Ru heterostructures supported on γ-alumina. Unlike conventional transition and noble metal nanoparticles, the use of a pincer complex offers exceptional thermal stability due to its aryl backbone, which is advantageous for various endothermic dehydrogenation reactions of hydrocarbons in LOHCs. This pioneering hybrid catalyst is a novel approach, demonstrating a proof of concept. In this study, we utilized the hybrid catalyst to investigate the dehydrogenation and hydrogenation of a lower enthalpic system, specifically the cyclooctane-cyclooctene system. The dehydrogenation of cyclooctane was conducted at 443 K using tertiary butyl ethylene as a sacrificial hydrogen acceptor, while the hydrogenation of cyclooctene reaction catalyzed by Pd-Ru nanostructures occurred at 298 K and 1 atm H2. The results showed successful tandem dehydrogenation-hydrogenation reactions. However, challenges were noted in terms of catalytic activity and recyclability, providing valuable insights for further refinement and optimization.

Mycodegradation of low-density polyethylene by Cladosporium sphaerospermum, isolated from platisphere.

Plastic accumulation is a severe threat to the environment due to its resistivity to thermal, mechanical and biological processes. In recent years, microbial degradation of plastic waste disposal is of interest because of its eco-friendly nature. In this study, a total of 33 fungi were isolated from the plastisphere and out of which 28 fungal species showed halo zone of clearance in agarized LDPE media. The fungus showing highest zone of clearance was further used to evaluate its degradation potential. Based on morphological and molecular technique, the fungus was identified as Cladosporium sphaerospermum. The biodegradation of LDPE by C. sphaerospermum was evaluated by various methods. The exposure of LDPE with C. sphaerospermum resulted in weight loss (15.23%) in seven days, higher reduction rate (0.0224/day) and lower half-life (30.93 days). FTIR analysis showed changes in functional group and increased carbonyl index in LDPE treated with C. sphaerospermum. SEMimages evidenced the formation of pits, surface aberrations and grooves on the LDPE film treated with the fungus whereas the untreated control LDPE film showed no change. AFM analysis confirmed the surface changes and roughness in fungus treated LDPE film. This might be due to the extracellular lignolytic enzymes secreted by C. sphaerospermum grown on LDPE. The degradation of polyethylene by Short chain alkanes such as dodecane, hexasiloxane and silane were identified in the extract of fungus incubated with LDPE film through GC-MS analysis which might be due to the degradation of LDPE film by C. sphaerospermum. This was the first report on the LDPE degradation by C. sphaerospermum in very short duration which enables green scavenging of plastic wastes.

Isolated Papillary Thyroid Carcinoma of the Pyramidal Lobe: A Case Report and Review of Literature.

The pyramidal lobe (PL) represents an embryological remnant of the thyroglossal duct. A solitary focus of papillary thyroid carcinoma (PTC) of the PL of thyroid gland is a rare entity. We present a case of a 33-year-old woman with PTC of the PL with lymph nodal involvement and further discuss the lines of surgical management for primary PTC arising from the PL of thyroid gland.

PAEDIATRIC SYMPTOMATIC SEIZURES IN INDIA: UNRAVELLING VARIED ETIOLOGIES AND NEUROIMAGING PATTERNS - A MULTICENTRIC STUDY.

Pediatric neuroimaging presents a unique set of challenges, primarily stemming from the intricacies of normal myelination processes occurring within the initial two years of life. This complexity is particularly pronounced in the context of pediatric epilepsy, where a substantial proportion of neuroimaging cases appears normal, especially in instances of idiopathic or provoked seizures. Nevertheless, abnormalities in neuroimaging tend to manifest in cases of acute or remote symptomatic seizures. Notably, the etiological landscape of seizures in children diverges significantly from that observed in adults, with neurodevelopmental, neurometabolic, and neuro-infectious factors emerging as predominant contributors. This multicentric study, conducted between November 2021 and November 2023, spanned diverse hospitals across various states in India. Encompassing children from birth to 12 years of age experiencing acute and remote symptomatic seizures, the study meticulously documented clinical and demographic profiles. Exclusion criteria were applied, excluding typical febrile seizures and idiopathic epilepsy syndromes to ensure a focused analysis. The study encompassed a total of 109 cases, revealing a spectrum of neuroimaging findings. Noteworthy among these were cortical malformations, including focal cortical dysplasia (12 cases), tuberous sclerosis (6 cases), polymicrogyria (3 cases), hemimegalencephaly (1 case), lissencephaly (1 case), schizencephaly (2 cases), heterotopias (3 cases), cavernous hemangioma (1 case), and AV malformation (1 case). Additionally, neoplastic lesions (6 cases), neurocysticercosis (5 cases), tuberculoma (4 cases), hippocampal sclerosis (3 cases), post-hypoxic and cerebrovascular accident gliosis (3 cases), leukodystrophies (2 cases), and non-lesional cases (58 cases) were documented. Pediatric neuroimaging in symptomatic seizures may present with normal findings, influenced by interpreter bias and the non-uniform availability of 3T MRI across different medical centers. The diverse causative factors for symptomatic seizures underscore the impact of demographic features, including the endemicity of specific infections and birth injuries, on the observed variability across medical centers. These findings underscore the imperative for a comprehensive understanding and standardization in pediatric neuroimaging practices.

Monodisperse Ag, Au Nanoparticles via Solvated Metal Atom Dispersion and Digestive Ripening in Ionic Liquid.

Digestive ripening (DR) is a postsynthetic protocol for the transformation of a colloid consisting of polydisperse metal nanoparticles (NPs) into a colloid composed of nearly monodisperse metal nanoparticles. This process is brought about by the digestive ripening agent, typically an organic ligand with a long alkyl chain at one end and a functional group at the other, at the boiling point of the solvent in which it is carried out, requiring long periods of time. In this work, digestive ripening of polydisperse Ag and Au nanoparticles brought about by ionic liquids (ILs) under very mild conditions (∼273 K, ∼30 min) to obtain nearly monodisperse nanoparticles has been demonstrated. Herein, the ionic liquid plays a dual role, as a digestive ripening and a stabilizing agent for the nanoparticles. Ionic liquid-assisted digestive ripening under such mild temperatures and short period of time has hitherto not been reported.

Shape and Phase-Controlled One-Pot Synthesis of Air Stable Cationic AgCdS Nanocrystals, Optoelectronic and Electrochemical Hydrogen Evolution Studies.

CdS-based materials are extensively studied for photocatalytic water splitting. By incorporating Ag+ into CdS nanomaterials, the catalyst's charge carrier dynamic can be tuned for photo-electrochemical devices. However, photo-corrosion and air-stability of the heterostructures limit the photocatalytic device's performance. Here, a one-pot, single molecular source synthesis of the air-stable AgCdS ternary semiconductor alloy nanostructures by heat-up method is reported. Monoclinic and hexagonal phases of the alloy are tuned by judicious choice of dodecane thiol (DDT), octadecyl amine (ODA), and oleyl amine (OLA) as capping agents. Transmission electron microscope (TEM) and powder X-ray diffraction characterization of the AgCdS alloy confirm the monoclinic and hexagonal phase (wurtzite) formation. The high-resolution TEM studies confirm the formation of AgCdS@DDT alloy nanorods and their shape transformation into nano-triangles. The nanoparticle coalescence is observed for ODA-capped alloys in the wurtzite phase. Moreover, OLA directs mixed crystal phases and anisotropic growth of alloy. Optical processes in AgCdS@DDT nano-triangles show mono-exponential decay (3.97 ± 0.01 ns). The monoclinic phase of the AgCdS@DDT nanorods exhibits higher electrochemical hydrogen evolution activity in neutral media as compared to the AgCdS@ODA/OLA alloy nanocrystals. DDT and OLA-capped alloys display current densities of 14.1 and 14.7 mA cm-2 , respectively, at 0.8 V (vs RHE).

H-atom site exchange in an iridium trans-dihydrogen/hydride complex, trans-[Ir(H)(η2-H2)(iPr)4(POCOP)(DMAP)].

Treatment of trans-[Ir(H)(N)2(iPr)4(POCOP)(DMAP)][BAr4f] (2) with H2 (1 bar) under ambient conditions (298 K) results in the formation of a trans-[Ir(H)(η2-H2)(iPr)4(POCOP)(DMAP)][BAr4f] (3) complex. Complex 3 exhibits H-atom site exchange between the bound H2 and the hydride ligands which are mutually trans to one another. A plausible mechanism of this exchange involves metal-ligand cooperativity as studied by computations.

Acetylene Semi-Hydrogenation at Room Temperature over Pd-Zn Nanocatalyst.

A reaction of fundamental and commercial importance is acetylene semi-hydrogenation. Acetylene impurity in the ethylene feedstock used in the polyethylene industry poisons the Ziegler-Natta catalyst which adversely affects the polymer quality. Pd based catalysts are most often employed for converting acetylene into the main reactant, ethylene, however, it often involves a tradeoff between the conversion and the selectivity and generally requires high temperatures. In this work, bimetallic Pd-Zn nanoparticles capped by hexadecylamine (HDA) have been synthesized by co-digestive ripening of Pd and Zn nanoparticles and studied for semi-hydrogenation of acetylene. The catalyst showed a high selectivity of ~85 % towards ethylene with a high ethylene productivity to the tune of ~4341 µmol g-1 min-1 , at room temperature and atmospheric pressure. It also exhibited excellent stability with ethylene selectivity remaining greater than 85 % even after 70 h on stream. To the best of the authors' knowledge, this is the first report of room temperature acetylene semi-hydrogenation, with the catalyst effecting high amount of acetylene conversion to ethylene retaining excellent selectivity and stability among all the reported catalysts thus far. DFT calculations show that the disordered Pd-Zn nanocatalyst prepared by a low temperature route exhibits a change in the d-band center of Pd and Zn which in turn enhances the selectivity towards ethylene. TPD, XPS and a range of catalysis experiments provided in-depth insights into the reaction mechanism, indicating the key role of particle size, surface area, Pd-Zn interactions, and the capping agent.

Phase-Controlled Pd-Sn Nanostructures via Co-Digestive Ripening: Catalytic Performance for Base-Free Oxidation of Benzyl Alcohol.

Diluting the precious metal to be used for catalysis with an abundant and non-precious metal to form alloy/intermetallic nanostructures is of great interest owing to the cost-effectiveness of the catalyst. The physicochemical properties of such bimetallic nanostructures are influenced by the atomic ordering of different atoms in the system, generally enhancing the catalytic activity, selectivity, and durability compared to their monometallic counterparts. To understand the relationship between the structure and the activity of the catalyst, phase-controlled synthesis of alloy/intermetallic nanostructures is crucial. Easy and scalable synthesis of such nanostructures with phase control presents a true challenge. We exploited a colloidal-based synthetic route termed 'co-digestive ripening' to prepare Pd-Sn alloy/intermetallic nanostructures. Oleylamine capped Pd and Sn colloids were utilized to obtain network-like Pd3 Sn and grape-like Pd2 Sn nanostructures. Temperature and the stoichiometric ratio between Pd and Sn played significant roles in achieving phase control. The mixture of ligands (oleylamine and trioctylphosphine) in the synthetic procedure resulted in the formation of well-separated nanoparticles (2.9±0.5 nm) in the case of Pd3 Sn and few nm-sized particles along with aggregates in the case of Pd2 Sn. Pd-Sn nanostructures showed enhanced activity and selectivity as compared to their monometallic counterparts for the catalytic performance towards oxidation of benzyl alcohol.

Molecular characterization and serodiagnostic evaluation of the Echinococcus ortleppi recombinant glutaredoxin 1 protein for cystic echinococcosis in buffalo (Bubalus bubalis).

Cystic echinococcosis (CE), caused by the metacestode of Echinococcus granulosus sensu lato (s.l.), adversely affects the physiology of the vital organs in which they grow. Condemnation of meat causes substantial economic loss to the livestock industry. Conventionally the infection is detected by necropsy as serological diagnosis of the infection in livestock is ambiguous. Identification of specific diagnostic antigens would be a substitute for the cyst fluid antigens which lack adequate diagnostic sensitivity and specificity. BLAST analysis supported by the negligible pairwise nucleotide distance of the 389 nt COX1, 489 nt NAD1, and 425 nt ITS1 with the related sequences of E. ortleppi ascertained the association of E. ortleppi with CE in buffaloes. Given the extensive distribution of glutaredoxin 1 in every developmental stage of Echinococcus granulosus s.l that makes it an ideal serodiagnostic antigen for CE, we expressed the 14 kDa E. ortleppi glutaredoxin 1 (rEoGrx1) protein in E. coli BL21 (DE3) and tested a total of 225 sera samples, including 126 sera samples from the necropsy-positive buffalo, by the rEoGrx1 IgG-ELISA. The ELISA could detect a total of 82/126 sera samples as positive. The diagnostic sensitivity and specificity of the rEoGrx1 IgG-ELISA were 65.1 % and 51.5 %, respectively. The protein showed serological cross-reaction against Fasciola gigantica, Toxoplasma gondii, and Sarcocystis sp. The in silico bioinformatics analysis of the E. ortleppi, F. gigantica, and T. gondii glutaredoxin sequences revealed fully conserved amino acids at positions 11 and 21, the substitution of conserved amino acids at positions 14 and 6, and semi-conserved substitutions at positions 3 and 4, respectively. The findings partly explain the molecular basis of the serological cross-reactivity of the protein.

Multi-functional palladium-ruthenium nanocomposites: an approach towards semi-hydrogenation catalysis and hydrogen sorption.

Development of heterogeneous metal catalysts with superior activity and high selectivity towards the semi-hydrogenation of alkynes is of significant industrial importance. Bimetallic Pd-Ru nanocomposites were synthesized over the entire composition range using a capping-agent assisted solution-based approach. The as-prepared nanocomposites demonstrated excellent catalytic activity towards the hydrogenation of a wide range of olefinic substrates and exceptional selectivity towards styrene in a phenylacetylene semi-hydrogenation reaction under mild conditions. In addition, hydrogen sorption studies were performed on the as-prepared bimetallic Pd-Ru nanomaterials, where an increase in the incorporation of Ru atoms into the bimetallic structure resulted in a decrease in the hydrogen storage capacity of the resulting material. Comprehensive structural characterization and insights obtained from the hydrogen sorption studies revealed that the presence of weakly bound hydrogen atoms in the hydride phase of the bimetallic species contributes to its excellent selectivity in hydrogenation reactions.

Co-digestive ripening assisted phase-controlled synthesis of Ag-Sn intermetallic nanoparticles and their dye degradation activity.

The Ag-Sn based system in the nano-size regime is one of the strongest candidates for lead-free solders. Besides, the investigation of several other applications of Ag-Sn nanostructures, especially in catalysis, remains scarce which makes it an interesting system to synthesize and explore its chemistry. In this report, nearly monodisperse ε-Ag3Sn intermetallic nanoparticles were prepared by a simple and convenient solution-based process of co-digestive ripening using Ag and Sn colloids obtained by the solvated metal atom dispersion (SMAD) method. Optimization of the temperature and stoichiometric ratio between the metal elements and the use of an appropriate capping agent are crucial factors to realise phase pure intermetallic nanoparticles. Ag3Sn nanoparticles with a size of 3.8 nm ± 0.6 nm were obtained within 12 h of reaction when tri-n-octylphosphine/tri-n-octylphosphine oxide was used as the capping agent at 205 °C. Interestingly, Ag3Sn@SnOx core-shell nanostructures were obtained by changing the capping agent to palmitic acid. These nanostructures were thoroughly characterized by powder X-ray diffraction, transmission electron microscopy (TEM and STEM-EDS), X-ray photoelectron spectroscopy and optical spectroscopy. Thereafter, Ag and Ag3Sn nanoparticles were utilized for photocatalytic degradation of methylene blue, methyl orange and a mixture of both the dyes.

An insight into the sodium-ion and lithium-ion storage properties of CuS/graphitic carbon nitride nanocomposite.

Metal sulfides are gaining prominence as conversion anode materials for lithium/sodium ion batteries due to their higher specific capacities but suffers from low stability and reversibility issues. In this work, the electrochemical properties of CuS anode material has been successfully enhanced by its composite formation using graphitic carbon nitride (g-C3N4). The CuS nanoparticles are distributed evenly in the exfoliated g-C3N4 matrix rendering higher electronic conductivity and space for volume alterations during the repeated discharge/charge cycles. The 0.8CuS:0.2g-C3N4 composite when used as an anode for lithium ion coin cell exhibits a reversible capacity of 478.4 mA h g-1 at a current rate of 2.0 A g-1 after a run of 1000 cycles which is better than that reported for CuS composites with any other carbon-based matrix. The performance is equally impressive when 0.8CuS:0.2g-C3N4 composite is used as an anode in a sodium ion coin cell and a reversible capacity of 408 mA h g-1 is obtained at a current rate of 2.0 A g-1 after a run of 800 cycles. A sodium ion full cell with NVP cathode and 0.8CuS:0.2g-C3N4 composite anode has been fabricated and cycled for 100 runs at a current rate of 0.1 A g-1. It can be inferred that the g-C3N4 matrix improves the ion transfer properties, alleviates the volume alteration happening in the anode during the discharge/charge process and also helps in preventing the leaching of polysulfides generated during the electrochemical process.

Width and thickness of the gingiva in periodontally healthy individuals in a central Indian population: a cross-sectional study.

OBJECTIVES: The present study was performed to determine the gingival dimensions (width and thickness) among young individuals in a central Indian population. MATERIALS AND METHODS: Periodontal probing depth, width of the keratinized and attached gingiva, and gingival thickness were recorded on maxillary and mandibular teeth from central incisor to first molar unilaterally in 75 systemically healthy individuals (32 males and 43 females; 19-30 years of age). Comparisons were made gender-wise, arch-wise, tooth-wise, and site-wise using either the Student's t test or the ANOVA. RESULTS: Keratinized and attached gingiva were wider in the maxilla than in the mandible both at proximal and at mid-buccal aspects (p < 0.001). At the tooth level also, gingiva was wider at the maxillary teeth than the corresponding mandibular teeth and at proximal aspects than at the mid-buccal aspect (p < 0.001). Regarding the thickness, gingiva was thicker among males, in the mandible, and at inter-proximal sites (p < 0.001). In either arch, maximum thickness was observed at the incisor region and least at the canine region. CONCLUSIONS: Dimensions of the gingival tissues vary between different populations and between different areas of the dentition within the same subject. These variations need to be better understood because these aspects may have an important bearing on periodontal treatment planning as width and thickness of gingiva are important in terms of maintenance of periodontal health. CLINICAL RELEVANCE: The dimensions of the clinically healthy gingiva are important in clinical practice as they can influence the progression of periodontal disease as well as impact the outcome of periodontal and restorative and orthodontic therapy.

Formation and weathering assessment of oil-suspended sediment aggregates through a laboratory investigation.

Formation of oil-suspended sediment aggregates (OSAs) is believed to be one of the natural cleaning processes in the marine environment. In this study, we have investigated the formation processes of OSAs under different mixing periods (continuous mixing and with the addition of sediments in between), oil-sediment ratios (1:1, 1:2 and 2:1) and crude oils (Arabian Light (AL), Kuwait (KW) and Murban (MB)). The results revealed that size of OSAs significantly increased (up to ≈ 1.41 mm) with the addition of sediments. Aggregates (total 36) were extracted for n-alkanes and polycyclic aromatic hydrocarbons to quantify and assess their weathering and toxic levels. The maximum n-alkane depletion was 84% (111-02), 94% (212-02) and 84% (321-02) and PAH depletion was ≈ 72% (111-02), 79% (212-02) and 81% (311-03) for the OSAs of AL, KW and MB crude oils, respectively, for the different samples considered, indicating that n-alkanes were depleted relatively higher than the PAHs. The highest depletion of both n-alkane and PAHs has occurred in OSAs of 10-h continuous mixing. The depletion of both n-alkane and PAHs reduced after the addition of sediments, however, escalated the growth of OSAs, resulting in bigger size OSAs. The concentration of PAHs of all 36 OSAs is greater than 5000 ng/g, indicating very high PAH pollution. Though the formation of OSAs helps in cleaning the spill sites, the carcinogenic threat to the marine ecosystem caused by these OSAs cannot be ignored.

Prevalence of Periodontal Disease and Oral Hygiene Practices in Kancheepuram District Population: An Epidemiological Study.

BACKGROUND AND OBJECTIVES: The purpose of the study was to evaluate the prevalence of periodontal disease status and oral hygiene practices in urban and rural population of Kancheepuram District, Tamil Nadu, India. METHODS: This epidemiological survey was carried out on 1650 participants taken from both urban and rural areas of Kancheepuram District. The study groups will belong to rural and urban areas in the ratio of 1:2, respectively. Every individual was assessed with the oral hygiene index-simplified, community periodontal index of treatment needs and periodontal disease index. In addition, the oral hygiene practices were also studied and recorded in a specially designed pro forma. Data were subjected to statistical analysis using SPSS 19.0 software. RESULTS: The study showed that 50% and 36% of the study participants have gingivitis and periodontitis, respectively, while only 14% of the study participants did not present with any form of periodontal disease. The study also showed that 16.63% of the study subjects among urban and 7.63% of them among rural do not have any type of periodontal disease. About 57.09% of the study participants among urban and 36.54% of the study participants among rural areas have gingivitis. The remaining 26.3% of the study participants in urban areas and 55.8% of the study participants in rural areas have periodontitis. It was observed that majority of participants brush once a day using Medium bristle tooth brush and toothpaste as dentifrice. CONCLUSION: Periodontal disease is widely spread among population of Kancheepuram District, with greater prevalence in rural population than in urban population. This could be mainly due to the lack of awareness and limited availability of resources. These estimates are vital for the future planning of dental services in Kancheepuram District, Tamil Nadu, India.

Photocatalytic, antiproliferative and antimicrobial properties of copper nanoparticles synthesized using Manilkara zapota leaf extract: A photodynamic approach.

Copper nanoparticles were synthesized using Manilkara zapota leaf extract. The synthesis of the nanoparticle was primarily visualized when the colour of the reaction mixture turned into reddish-brown. Biosynthesized nanoparticles were characterized by UV-vis, FT-IR, XRD, SEM and EDX. The UV spectra showed maximum absorption at 584 nm. FT-IR studies showed stretching frequency at 592.76 cm-1, which is the fingerprint region for Cu-O bond. The crystallinity of the synthesized copper nanoparticles (Mz-Cu NPs) was revealed through XRD analysis. The synthesized Mz-Cu NPs were spherical with an average size of 18.9-42.5 nm and it was shown by SEM analysis. EDX analysis displayed that the nano sample contains 58 % of copper. The antimicrobial property of the synthesized nanoparticles was evaluated against fungal plant pathogens Rhizoctonia solani (MTCC 12232), Sclerotium oryzae (MTCC 12230) and bacterial species, namely Bacillus subtilis (ATCC 23857), Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Vibrio harveyi (ATCC 35084), Vibrio parahaemolyticus (ATCC 33845). In in-vitro haemolytic assay, the particle showed 5.73, 3.34, 0.5 % hemolysis at 100, 50, 25 µg/mL concentration respectively. In the antiproliferative assay, the IC50 values of MCF7 and Vero cells were found to be 53.89 and 883.69 µg/µl. The particle degraded Methyl violet, Malachite green and Coomassie brilliant blue by 92.2, 94.9 and 78.8 %, within 50, 40 and 60 min, respectively, through its photocatalytic activity.