[The properties of the Vibrio cholerae strains isolated in large districts in western Dagestan in 1994]. / Svoistva shtammov Vibrio cholerae, vydelennykh v krupnykh raionakh na zapade Dagestana v 1994 g.

190 V. cholerae cultures isolated by the specialized antiepidemic brigade of the Rostov-on-Don Research Institute for Plague Control in the Khasavyurt, Babayurt and Novolaksk regions of Daghestan in August-October 1994. All isolated strains were typical with respect to their morphological and cultural properties and could be agglutinated (with the exception of one strain) to the titer or half-titer with diagnostic cholera serum and Ogawa serum. 4 strains had signs of RO-dissociation, 4 strains were agglutinated with Inaba serum in a low titer. All strains were resistant to diagnostic bacteriophages. Cyproxin and doxicycline proved to be the most active agents for the treatment of patients. Agglutinins, vibriocidins and antidermonectrotic antibodies in diagnostic titers were detected in the sera of all patients and Vibrio carriers.

[The agglutinability of cholera O-monoclonal immunoglobulins]. / K voprosu ob aggliutinabel'nosti kholernykh O-monoklonal'nykh immunoglobulinov.

A set of 10 monoclonal antibodies specific for vibrio species and of 5 monoclonal antibodies specific for serovar (Ogawa) was studied. These monoclonal antibodies were directed toward V. cholerae O1 antigen in agglutination reaction and on slide plates. Monoclonal antibodies agglutinating typical strains of cholera vibrios with titration range from 1: 6000 to 1: 25,000 were selected. MA were revealed to interact with cholera vibrio strains with reduced agglutinability. The set of agglutinating O monoclonal immunoglobulins was developed for laboratory identification of cholera O1 vibrios.