Looking through Providers' Eyes: Pain in the Neonatal Intensive Care Unit.

OBJECTIVE: Evaluate the pain of critically ill newborns is a challenge because of the devices for cardiorespiratory support. This study aim to verify the adults' gaze when assessing the critically ill neonates' pain at bedside. STUDY DESIGN: Cross-sectional study in which pediatricians, nursing technicians, and parents evaluated critically ill neonates' pain at bedside, for 20 seconds with eye-tracking glasses. At the end, they answered whether the neonate was in pain or not. Visual tracking outcomes: number and time of visual fixations in four areas of interest (AOI) (face, trunk, and upper [UL] and lower [LL] limbs) were compared between groups and according to pain perception (present/absent). RESULTS: A total of 62 adults (21 pediatricians, 23 nursing technicians, 18 parents) evaluated 27 neonates (gestational age: 31.8 ± 4.4 weeks; birth weight: 1,645 ± 1,234 g). More adults fixed their gaze on the face (96.8%) and trunk (96.8%), followed by UL (74.2%) and LL (66.1%). Parents performed a greater number of fixations on the trunk than nursing technicians (11.0 vs. 5.5 vs. 6.0; p = 0.023). Controlled for visual tracking variables, each second of eye fixation in AOI (1.21; 95% confidence interval [CI]: 1.03-1.42; p = 0.018) and UL (1.07; 95% CI: 1.03-1.10; p < 0.001) increased the chance of perceiving the presence of pain. CONCLUSION: Adults, when assessing at bedside critically ill newborns' pain, fixed their eyes mainly on the face and trunk. The time spent looking at the UL was associated with the perception of pain presence. KEY POINTS: · Pain assessment in critically ill newborns is a challenge.. · To assess critically ill neonates' pain, adults mainly look at the face and trunk.. · Looking at the upper limbs also helps in assessing critically ill neonates' pain..

Operational Challenges in the Use of Structured Secondary Data for Health Research.

Background: In Brazil, secondary data for epidemiology are largely available. However, they are insufficiently prepared for use in research, even when it comes to structured data since they were often designed for other purposes. To date, few publications focus on the process of preparing secondary data. The present findings can help in orienting future research projects that are based on secondary data. Objective: Describe the steps in the process of ensuring the adequacy of a secondary data set for a specific use and to identify the challenges of this process. Methods: The present study is qualitative and reports methodological issues about secondary data use. The study material was comprised of 6,059,454 live births and 73,735 infant death records from 2004 to 2013 of children whose mothers resided in the State of São Paulo - Brazil. The challenges and description of the procedures to ensure data adequacy were undertaken in 6 steps: (1) problem understanding, (2) resource planning, (3) data understanding, (4) data preparation, (5) data validation and (6) data distribution. For each step, procedures, and challenges encountered, and the actions to cope with them and partial results were described. To identify the most labor-intensive tasks in this process, the steps were assessed by adding the number of procedures, challenges, and coping actions. The highest values were assumed to indicate the most critical steps. Results: In total, 22 procedures and 23 actions were needed to deal with the 27 challenges encountered along the process of ensuring the adequacy of the study material for the intended use. The final product was an organized database for a historical cohort study suitable for the intended use. Data understanding and data preparation were identified as the most critical steps, accounting for about 70% of the challenges observed for data using. Conclusion: Significant challenges were encountered in the process of ensuring the adequacy of secondary health data for research use, mainly in the data understanding and data preparation steps. The use of the described steps to approach structured secondary data and the knowledge of the potential challenges along the process may contribute to planning health research.

Discordância entre pais e profissionais de saúde quanto à intensidade da dor no recém-nascido criticamente doente / Disagreement between parents and health professionals regarding pain intensity in critically ill neonates

OBJETIVO: Verificar se pais e profissionais de saúde que trabalham em unidades de terapia intensiva neonatal avaliam de maneira semelhante a presença e a magnitude da dor no recém-nascido (RN). MÉTODOS: Estudo transversal com 52 RN e 154 adultos. Os critérios de inclusão foram: internação em unidade de terapia intensiva neonatal, presença de sonda gástrica, cânula traqueal e acesso venoso. Cada RN foi observado de modo simultâneo por um trio diferente de adultos (pai/mãe, pediatra e auxiliar de enfermagem) durante 1 minuto para avaliar presença e intensidade da dor do paciente. A análise quanto à homogeneidade da avaliação de dor foi realizada por meio do gráfico de Bland-Altman modificado e do coeficiente de correlação intraclasses (CCI). A associação de fatores próprios do recém-nascido com a heterogeneidade da avaliação da dor do RN pelos adultos foi avaliada por meio de regressão linear múltipla. RESULTADOS: O CCI mostrou discordância entre os três grupos de adultos quanto à avaliação da dor (CCI 0,066, concordância > 0,75). A análise de Bland-Altman mostrou que houve concordância entre os adultos quanto à ausência de dor no RN. Porém, quando os adultos achavam que a dor estava presente, houve heterogeneidade na avaliação da intensidade de dor neonatal. A análise de regressão múltipla indicou que apenas 10 por cento desta heterogeneidade foi explicada pelo sexo e via de parto do RN. CONCLUSÕES: A heterogeneidade na avaliação feita por adultos da intensidade da dor de RN é um marcador da dificuldade de se decidir a respeito da necessidade de analgesia em pacientes pré-verbais.

OBJECTIVE: To verify whether parents and health professionals homogeneously evaluate presence and intensity of neonatal pain. METHODS: This cross-sectional study enrolled 52 neonates and 154 adults. Inclusion criteria for neonates were admission to neonatal intensive care unit, presence of gastric tube, tracheal tube, and venous lines. Each newborn was observed by a different group of three adults (parent, nurse assistant and pediatrician) for 1 minute at the same time to evaluate presence and intensity of infant's pain. Homogeneity of pain evaluation was analyzed by a modified Bland-Altman plot and by intraclass correlation coefficient (ICC). Multiple linear regression analysis was used to evaluate association of neonatal characteristics and heterogeneity of pain scores for adults. RESULTS: ICC showed disagreement of the pain scores given by the three groups of adults (ICC 0.066, agreement > 0.75). Bland-Altman analysis showed agreement among adults when they thought pain was absent. When they thought pain was present, there was heterogeneity of opinions regarding intensity of neonatal pain. Multiple regression analysis indicated that 10 percent of this disagreement could be explained by infant's gender and mode of delivery. CONCLUSIONS: Disagreement among adults about intensity of neonatal pain is a marker of the difficulty in deciding the need for analgesia in preverbal patients.

Disagreement between parents and health professionals regarding pain intensity in critically ill neonates.

OBJECTIVE: To verify whether parents and health professionals homogeneously evaluate presence and intensity of neonatal pain. METHODS: This cross-sectional study enrolled 52 neonates and 154 adults. Inclusion criteria for neonates were admission to neonatal intensive care unit, presence of gastric tube, tracheal tube, and venous lines. Each newborn was observed by a different group of three adults (parent, nurse assistant and pediatrician) for 1 minute at the same time to evaluate presence and intensity of infant's pain. Homogeneity of pain evaluation was analyzed by a modified Bland-Altman plot and by intraclass correlation coefficient (ICC). Multiple linear regression analysis was used to evaluate association of neonatal characteristics and heterogeneity of pain scores for adults. RESULTS: ICC showed disagreement of the pain scores given by the three groups of adults (ICC 0.066, agreement > 0.75). Bland-Altman analysis showed agreement among adults when they thought pain was absent. When they thought pain was present, there was heterogeneity of opinions regarding intensity of neonatal pain. Multiple regression analysis indicated that 10% of this disagreement could be explained by infant's gender and mode of delivery. CONCLUSIONS: Disagreement among adults about intensity of neonatal pain is a marker of the difficulty in deciding the need for analgesia in preverbal patients.

[The frequency of pharmacological pain relief in university neonatal intensive care units]. / Freqüência do emprego de analgésicos em unidades de terapia intensiva neonatal universitárias.

OBJECTIVE: To evaluate the use of drugs to relieve procedural pain of newborn infants hospitalized in Neonatal Intensive Care Units (NICU) of university hospitals. METHODS: A prospective cohort study of all newborn infants hospitalized in four NICU during October 2001. The following data were collected: demographic data of patients; clinical morbidity; number of potentially painful procedures and frequency of analgesic administration. Multiple linear regression analysis was performed to study the factors associated with the use of analgesia in this cohort of patients with SPSS 8.0. RESULTS: Ninety-one newborn infants were admitted to the NICU during the study period (1,025 patient-days). Only 25% of the 1,025 patient-days received any systemic analgesia. No specific drug was administered to relieve acute pain during any of the following painful procedures: arterial, venous, capillary and lumbar punctures and tracheal intubation. For chest tube insertion, 100% of newborn infants received specific analgesia. For the insertion of central catheters, 8% of the newborn infants received analgesia. Only nine of the 17 newborn infants that underwent surgical procedures received any dose of analgesics during the postoperative period. Regarding patients who received analgesia, the drug of choice was fentanyl in 93%. The presence of mechanical ventilation increased 6.9 times the chance of the newborn receiving analgesia and the presence of a chest tube increased this chance by 5.0 times. CONCLUSION: It is necessary to train health professionals in order to shorten the lag between scientific knowledge regarding newborn pain and clinical practice.

Freqüência do emprego de analgésicos em unidades de terapia intensiva neonatal universitárias / The frequency of pharmacological pain relief in university neonatal intensive care units

OBJETIVO: Verificar a freqüência com que são empregados analgésicos para o alívio da dor desencadeada por procedimentos invasivos em recém-nascidos internados em UTI universitárias e verificar o perfil de uso de medicamentos para o alívio da dor. MÉTODOS: Coorte prospectiva, avaliada entre 1° e 31 de outubro de 2001, de todos os recém-nascidos internados em quatro UTI. Dados coletados: características gerais das unidades; dados demográficos dos recém-nascidos; morbidade clínica e freqüência do emprego de analgésicos. Realizaram-se a análise estatística descritiva e a regressão linear múltipla por meio do SPSS 8.0, para analisar os fatores associados ao uso de analgésicos nesta coorte. RESULTADOS: No período, foram internados 91 recém-nascidos (1.025 pacientes-dia). Apenas 25 por cento dos 1.025 pacientes-dia receberam alguma dose de analgésico por via sistêmica. Não foi administrada nenhuma medicação específica para o alívio da dor aguda durante os seguintes eventos dolorosos: intubações traqueais, punções arteriais, venosas, capilares e lombares. Na inserção de dreno de tórax, 100 por cento dos recém-nascidos receberam analgesia específica e, para a passagem de cateteres centrais, apenas 8 por cento. De 17 recém-nascidos submetidos a procedimentos cirúrgicos, somente nove receberam analgésicos no pós-operatório. O medicamento mais utilizado foi o fentanil (93 por cento). A presença de ventilação mecânica elevou em 6,9 vezes, e a de dreno de tórax em cinco vezes a chance do recém-nascido receber alguma dose de analgésico. CONCLUSÃO: Há necessidade de melhorar a formação dos profissionais de saúde para diminuir a distância entre os conhecimentos científicos existentes a respeito da dor no recém-nascido e a prática clínica.

[What do pediatricians know about pain assessment and treatment in newborn infants?]. / O que os pediatras conhecem sobre avaliação e tratamento da dor no recém-nascido?

OBJECTIVE: To analyze the knowledge of pediatricians who work with neonatal patients regarding the evaluation and treatment of pain in newborn infants. METHODS: Cross-sectional study of 104 pediatricians (out of 110) who were working during 1999 to 2001 in seven intensive care units and 14 nurseries in the city of Belém (Pará). The pediatricians answered a questionnaire about their demographic profile and their knowledge of pain evaluation and pain relief methods during the neonatal period. RESULTS: 100% of the pediatricians believed that newborns feel pain, but only one-third of them declared to know any scale for the evaluation of pain for this age group. The majority of the interviewees perceived the presence of pain in newborns by means of behavioral parameters. Crying was the preferential parameter to evaluate pain in full-term newborns; facial activity was the parameter chosen for premature infants; and heart rate for mechanically ventilated neonates. Less than 10% of the pediatricians reported using analgesia for venous and capillary puncture, while 30 to 40% said that they used analgesia for lumbar puncture, venous dissection, chest tube placement and mechanical ventilation. Less than half of those interviewed reported applying postoperative pain relief measures following abdominal surgery. Opioid was the most frequent medication for analgesia (60%), followed by midazolam (30%). CONCLUSION: These results demonstrate that it is necessary to refresh and update pediatricians' knowledge about pain assessment and relief.

O que os pediatras conhecem sobre avaliação e tratamento da dor no recém-nascido? / What do pediatricians know about pain assessment and treatment in newborn infants?

Objetivo: analisar os conhecimentos dos pediatras que atuam com pacientes neonatais em relação à avaliação e o tratamento da dor do recém-nascido. Método: estudo transversal com 104 pediatras (de um total de 110) que trabalhavam em 1999 a 2001, nas sete unidades de terapiaintensiva e nos 14 berçários da cidade de Belém, e responderam a um questionário escrito com perguntas a respeito do seu perfil demográfico e do conhecimento de métodos de avaliação e de tratamento da dor no recém-nascido. Resultados: cem por cento dos médicos referiram acreditar que o recém-nascido sente dor, mas apenas um terço deles conhecia alguma escala para avaliar a dor nessa faixa etária. A maioria dos entrevistados referia perceber a presença de dor no recém-nascidopor meio de parâmetros comportamentais. O choro foi o preferido para avaliar a dor do bebê a termo; a mímica facial para o prematuro, e a freqüência cardíaca para o neonato em ventilação mecanica.Menos de 10por cento dos entrevistados diziam usar analgesia para punções venosas e capilares; 30 a 40por cento referiam empregar analgesia para punções lombares, dissecações venosas, drenagens de tórax e ventilação mecânica. Menos da metade dos entrevistados referiu aplicar medidas para o alívio da dor no pós-operatório de cirurgia abdominal em neonatos. O opióide foi o medicamento mais citado para aanalgesia (60por cento), seguido pelo midazolam (30por cento).Conclusão: os pediatras demonstraram pouco conhecimento a respeito dos métodos de avaliação e tratamento da dor no período neonatal. Há necessidade de reciclagens e de atualização no tema para os profissionais de saúde que atuam com recém-nascidos doentes