RESUMO
Seven clinical cases of cutaneous papillomatosis in yaks were studied in Arunachal Pradesh, India. Sporadic, single or a chain of multiple varying size warts appeared around the eyes or on the body. Predominant site of warts was around eyes. Histopathologically, these cases were diagnosed as fibropapilloma. It was confirmed by the detection of BPV-1 and BPV-2 or their mixed infection by PCR and sequencing. Quantitative SYBR Green real-time PCR detected comparatively lower viral DNA copy number in cutaneous warts (CWs). Cases of CWs and its causative agent as bovine papillomavirus (BPVs) are reported for the first time in yaks.
Assuntos
Papillomavirus Bovino 1/isolamento & purificação , Doenças dos Bovinos/virologia , Deltapapillomavirus/isolamento & purificação , Papiloma/veterinária , Neoplasias Cutâneas/veterinária , Verrugas/veterinária , Animais , Papillomavirus Bovino 1/genética , Bovinos , Doenças dos Bovinos/diagnóstico , Doenças dos Bovinos/patologia , Coinfecção/patologia , Coinfecção/virologia , DNA Viral/análise , DNA Viral/genética , Deltapapillomavirus/genética , Feminino , Genes Virais , Índia , Masculino , Papiloma/patologia , Papiloma/virologia , Filogenia , Reação em Cadeia da Polimerase , Reação em Cadeia da Polimerase em Tempo Real , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/virologia , Verrugas/patologia , Verrugas/virologiaRESUMO
To test a hypothesis that the differences in running performances between men and women narrow with increasing race distance, recent best running speeds (m.s-1) of 28 female ultramarathon runners over racing distances from 5 to 90 km were compared with those of male runners matched for 56 km race time, age and training. These comparisons revealed that the men ran faster than the women over 5 to 42.2 km (P < 0.01-0.05), but not in a 90-km race (2.82 +/- 0.04 vs 2.90 +/- 0.09 m.s-1). Declines in the men's and women's running speeds with increasing race distances were best fitted by Y = 2.9.exp.(-0.01.X) + 1.7 and Y = 2.1.exp.(-0.01.X) + 2.0 equations (r = -0.99). Differences between the exponential declines in the men's and women's running speeds over longer race distances were best fitted by a linear Y = -0.006 (X-66) equation (r = -0.98, P < 0.001). The negative slope and the X-axis intercept of this equation at 66 km supports the hypothesis that women ultramarathon runners have greater fatigue resistance than do equally trained men whose performances are superior up to the marathon distance.