Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Gan To Kagaku Ryoho ; 49(13): 1455-1457, 2022 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-36733100

RESUMO

A woman in her 60s had been aware of perianal erosions for 1 month. Skin biopsy showed Paget's cells in the stratified squamous epithelium, and immunohistochemistry showed negative staining for CK7 and positive staining for CK20. Colonoscopy revealed well-differentiated adenocarcinoma in the anal canal. Computed tomography showed neither regional lymph node metastasis nor distant metastasis. Hence, she was diagnosed with anal canal carcinoma with pagetoid spread. We determined the extent of resection of the skin lesion preoperatively by mapping biopsy, and performed laparoscopic abdominoperineal resection. The pathological findings revealed adenocarcinoma(tub1, tub2), and the skin resection margin was negative. Immunohistochemistry for Paget's cells in the stratified squamous epithelium showed negative staining for GCDFP-15 and CK7, and positive staining for CK20. Twenty-four months after surgery, we detected right inguinal lymph node metastasis and performed right inguinal lymphadenectomy. As of 4 months after the lymphadenectomy, no local recurrence or distant metastasis has been detected during follow-up examinations.


Assuntos
Adenocarcinoma , Neoplasias do Ânus , Carcinoma de Células Escamosas , Laparoscopia , Doença de Paget Extramamária , Protectomia , Feminino , Humanos , Adenocarcinoma/cirurgia , Adenocarcinoma/patologia , Canal Anal/patologia , Neoplasias do Ânus/cirurgia , Neoplasias do Ânus/patologia , Carcinoma de Células Escamosas/cirurgia , Metástase Linfática/patologia , Doença de Paget Extramamária/cirurgia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...