Innovative methods measure the neural correlates of proprioception in multiple sclerosis.

The authors of the recently published article "Position sense deficits at the lower limbs in early multiple sclerosis: clinical and neural correlates" (Iandolo R, Bommarito G, Falcitano L, Schiavi S, Piaggio N, Mancardi GL, Casadio M, Inglese M. Neurorehabil Neural Repair 34: 260-270, 2020) provide strong evidence for the neural correlates leading to deficits in proprioception in multiple sclerosis. We believe their findings and innovative methodology show promise for how proprioception is measured in this and other clinical populations. We also suggest that further work should investigate the role of the corpus callosum in proprioceptive balance control.