1.
Chem Commun (Camb)
; 59(14): 1971-1974, 2023 Feb 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36722995
RESUMO
We developed a facile photoreductive and stereoselective ß-aminoalkylation of a crowded enone by blue LED light irradiation using a wide variety of α-amino acids in order to access 5'-amino substituted carbasugar nucleosides for SAM-based methyltransferase inhibitors. This photochemical method provides highly functionalized carbasugar mimics for nucleoside analogue synthesis.