RESUMO
OBJECTIVE: The objective of this study has been to examine antibiotic consumption in Spain through the use of the National Surveys of Health (NSH) . MATERIAL AND METHODS: Taking the NSH, between 1993 and 2003, certain variables regarding the consumption of antibiotics have been analyzed; putting these into groups according to their typology, habits, comorbidity and the utilization of health resources. This information has been compared with published data by other authors. RESULTS: The consumption of antibiotics was approximately 3%, and 9-19% of this was not prescribed. Significant statistical associations have been observed between the consumption of antibiotics and other aspects such as academic and income levels, habits such as smoking, general health, certain chronic diseases, being bed-ridden due to disease; and also the use of certain medicines and the anti-influenza vaccine. CONCLUSIONS: Consumption of antibiotics coincides with described data by other authors, and this was always higher than prescribed. The association with other variables may be limited by the inadequate NSH design in order to know the exact consumption of antibiotics.
Assuntos
Antibacterianos/provisão & distribuição , Adolescente , Adulto , Idoso , Prescrições de Medicamentos/estatística & dados numéricos , Uso de Medicamentos , Feminino , Recursos em Saúde/estatística & dados numéricos , Nível de Saúde , Inquéritos Epidemiológicos , Humanos , Vacinas contra Influenza , Masculino , Pessoa de Meia-Idade , Medicamentos sob Prescrição , Fatores Sexuais , Fatores Socioeconômicos , Espanha/epidemiologia , Adulto JovemRESUMO
Few patients have been reported with familial periodic paralysis and ventricular tachycardia. The natural history of these cases was unfavorable, with most dying because of a presumed cardiac dysrhythmia. We report for the first time the results of an electrophysiologic study of a similar case and the successful use of calcium channel blockers, shedding light on the possible mechanism and management of these patients.
Assuntos
Bloqueadores dos Canais de Cálcio/uso terapêutico , Paralisias Periódicas Familiares/complicações , Taquicardia Ventricular/tratamento farmacológico , Verapamil/uso terapêutico , Adolescente , Bloqueadores dos Canais de Cálcio/farmacologia , Eletrocardiografia , Teste de Esforço , Humanos , Masculino , Paralisias Periódicas Familiares/fisiopatologia , Taquicardia Ventricular/complicações , Taquicardia Ventricular/fisiopatologia , Verapamil/farmacologiaRESUMO
A patient is presented with hyperkalemic periodic paralysis (HyperPP) and a cardiac dysrhythmia. An amino acid substitution (Val783Ile) in the adult skeletal muscle sodium channel gene was detected. Although lack of available family members precluded rigorous genetic tests, the sodium channel change may be responsible for HyperPP in this patient and could also be responsible for the associated cardiac dysrhythmia.
