[The catalytic rate constant. Effect of acetone on acidic hydrolysis of ester cyclohexyl acidacetylomethyl (AmMC)]. / Kinetyka rozkladu leków. XCVI. Wplyw acetonu na szybkosc kwasowej hydrolizy estru acetylometylowego mecylinamu (AmMC).

The catalytic rate constants k(HCl) were established for hydrolysis of beta-lactam moiety in AmMC using equation k(obs) = k(H2O) + k(HCl)[HCl]. The estimate the effect of aceton the relation log k(HCl) = log kD + k Z(mu)/D was applied. The rate constant increases with the decrease of dielectric constant of the solvent.