[Preparations for serodiagnosis of diseases due to causative agents of ixode tick-borne Borreliosis (Lyme disease). Communication 2. Comparative study of recombinant enzyme immunoassay test-systems (rELISA) for serological diagnosis of ixode tick-borne Borreliosis]. / Preparaty dlia serodiagnostiki zabolevanii, vyzyvaemykh vozbuditeliami iksodovykh kleshchevykh borreliozov (bolezn' Laima). Soobshchenie 2. Sravnitel'naia otsenka rekombinantnykh immunofermentnykh test-sistem (rELISA), ispol'zuemykh v serodiagnostike iksodovykh kleshchevykh borreliozov.

One foreign and two Russian recombinant enzyme immunoassay test-systems were comparatively investigated under conditions of an encoded experiment. Sensitivity in the experiment with the Russian test-systems Borreliosis-ELISA-IgG and Lyme Best was 63.8 and 68.8% respectively. As for the test-system Borrelia IgG Recombinant, it was 47.5%. All the test-systems were highly specific (94.4 to 99.5%). The test-systems Lyme Best and Borrelia IgG Recombinant revealed partial cross reactions with sera from patients with systemic lupus erythematosus and leptospirosis.

[Ultrastructural analysis of pathological changes in ferrets with experimental canine distemper]. / Ul'trastrukturnyi analiz patologicheskikh izmenenii pri éksperimental'noi chume plotoiadnykh u khor'kov.

Morphologic study of the lungs, liver, spleen, and kidneys of ferrets infected with canine distemper virus has been carried out. Electron microscopy revealed virus reproduction in bronchial epithelial cells, types I and II alveolocytes, bile duct epitheliocytes, and hepatocytes. Mononuclear phagocyte system cells infected with the virus were found in all the examined organs. The most expressed pathological changes were observed in the lungs.

[The morphological changes in Ebola infection in guinea pigs]. / Morfologicheskie izmeneniia pri Ebola-infektsii u morskikh svinok.

Ebola virus reproduction and morphological lesions were investigated in infected guinea pigs by electron microscopy. The liver was found to be the main target organ, whereas in other internal organs the pathological changes were insignificant. Ebola virus reproduction was demonstrated only in cells of the mononuclear phagocyte system.